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Old Yesterday, 09:31 PM   #1
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DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing

Researchers developed ?DNA, a DNA-based CRISPR guide that allows Cas12 enzymes to target RNA with high specificity while retaining compatibility with DNA-editing workflows. The platform detected HCV RNA in clinical samples and enabled programmable RNA knockdown, multiplex targeting, and RNA modification in human cells.

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