response to herceptin after just one dose neoadjuvantly...

[Lani]

seems to change gene expression in such a way that they seem to be discovering biomarkers previously unknown to predict response to combination therapies in early breast cancer ie, before recurrence/hopefully preventing it!


4719 Dynamic changes in gene expression after one dose of trastuzumab (T) reveal novel biomarkers of response to combination therapy in HER2 positive early stage breast cancer. Lyndsay N. Harris, Emmett Sprecher, Lisa Wei-Gu, Kimberly Lezon- Geyda, Sudipa Sakar, Ian Krop, Eric P. Winer, David P. Tuck.

Another paper at the 2011 AACR annual meeting in Orlando coming soon!