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Old 08-23-2009, 02:15 PM   #1
bejuce
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Anyone took/taking Xeloda with radiation?

I had my bilateral mastectomy a couple of weeks ago after neoadjuvant chemo. The pathology report was mixed, showing on the positive side no tumor left in the breast tissue itself (and clear margins) but a lot of lymphatic invasion still present with 10 nodes positive (and this after a barrage of chemo!) I had one cycle of Herceptin before my surgery (to be continued for a year).

Because of the lymphatic presence and the aggressiveness of my tumor, my oncologist is thinking about adding Xeloda daily throughout my radiation treatments. Has anyone done that before? If so, was it worth it? How were the side effects? I'm not familiar with Xeloda, so any info you have will be much appreciated!

Thanks!!!

Marcia
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ER+ (30%)/PR-/HER-2+, stage 3

Diagnosed on 02/18/09 at 38 with a huge 12x10 cm tumor, after a 6 month delay. Told I was too young and had no risk factors. Found swollen node during breastfeeding.
March-August 09: neo-adjuvant chemo, part of a trial at Stanford (4 DD A/C, 4 Taxotere with daily Tykerb), loading dose of Herceptin
08/12/09 - bye bye boobies (bilateral mastectomy)
08/24/09 - path report shows 100 % success in breast tissue (no cancer there, yay!), 98 % success in lymphatic invasion, and even though 11/13 nodes were still positive, > 95 % of the tumor in them was killed. Hoping for the best!
September-October 09: rads with daily Xeloda
02/25/10 - Cholecystectomy
05/27/10 - Bone scan clear
06/14/10 - CT scan clear, ovarian cyst found
07/27/10 - Done with Herceptin!
02/15/11 - MVA-BN HER-2 vaccine trial
03/15/11 - First CA 15-3: 12.7 and normal, yay!
10/01/11 - Bone scan and CT scan clear, fatty liver found
now on Tamoxifen and Aspirin


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Old 08-23-2009, 03:56 PM   #2
Becky
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Location: Stockton, NJ
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Re: Anyone took/taking Xeloda with radiation?

Hi Marcia

I did not have Xeloda during rads but a friend from my local support group did. Initially, she had masectomy and chemo but got a local recurrence on the scar line later. She took 1000 mg Xeloda daily with rads. It intensified side effects - notably burning.

It does give a boost to the rads. So does Herceptin.
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Kind regards

Becky

Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia

NED 18 years!

Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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