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06-24-2008, 07:06 AM
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#1
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Senior Member
Join Date: Oct 2005
Location: Boise, Idaho
Posts: 758
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AI vs. Tamoxifen
I am having a lot of joint pain so asked my new medical onc about possibly changing. Her suggestion is to stop the arimidex and start tamoxifen. Last week I saw the radiation onc and she suggested aromasin.
I am at a loss about taking tamoxifen since I am almost 70 and have been post menopausal for over 30 years. Has this happened to anyone else? I am inclined to just keep taking the arimidex. I will see her in 2 weeks as the previous information was relayed over the phone by her nurse.
Any ideas or comments?
Love & hugs,
Marlys
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06-24-2008, 10:40 AM
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#2
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Senior Member
Join Date: Jul 2007
Location: Canada
Posts: 2,193
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Hi Marlys
I've gone through something similiar and decided to stay
on Arimidex. After 2 years, the joint pain has improved;
it's still there but I can live with it.
I just don't like the idea of going on Tamoxifen.
__________________
PinkGirl
Dx Aug/05 at age 51
2cm. Stage 2A, Grade 3
ER+/PR-
Her2 +++
Sept 7/05 Mastectomy
4 FAC, 4 Taxol, no radiation
1 year of Herceptin
Tamoxifen for approx. 4 months,
Arimidex for 5 years
Prophylactic mastectomy June 22/09
" I yam what I yam." - Popeye
My Photo Album
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06-24-2008, 07:59 PM
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#3
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Senior Member
Join Date: Oct 2006
Location: Louisville KY
Naples FL
Posts: 665
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I also was told I could go on Tamoxifen instead of
arimidex which is giving me bone and joint pain. I
decided to stick with it and have been swimming or
water walking and am feeling some better. I just
feel the arimidex is better for me. Maybe Femara
would be a good choice. I know it helped Jean.
patb
__________________
patb
Diagnosed June, 06, Stage I, Grade3, ER+PR- Her2positive, No Nodes. A/C X 4. Radiation 33 with boost, Herceptin every two weeks until Nov.
07, Arimedex for 5 years. Mugas and Echo and chest xRay. Bone scan of whole Body, and Back of Brain and spine MRI.
CT scan of Lungs every six months
due to two small places. December
2009, bone scan due to bone pain.
Follow up test in 2010.
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06-24-2008, 08:10 PM
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#4
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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Switching seems to help alot of women. Arimidex and Femara work in the same (biochemical) manner whereas Aromosin works differently. In the end, all 3 supress aromatase (that helps convert androgen to estrogen). Therefore, theory is that Aromosin would not cause the same side effects as Arimidex or Femara.
Why suffer if you can switch to another AI? Only you can answer to how you really physically feel and whether or not to switch or switch through all the AIs before trying out Tamoxifen.
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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06-26-2008, 04:22 AM
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#6
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Senior Member
Join Date: Jun 2007
Location: moved to Lancaster, Pa in June, 2010
Posts: 576
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I had problems with Arimidex, aromasin and then was switched to tamoxifen. Developed a rash from this. I am now on Femera and am happy to say the only side effect so far has been some sligtht weight gain. Like you I had already gone through menopause and questioned taking the tamoxifen, but as it turned out I was allergic to it anyway. Best of luck.
__________________
Debbie in North Carolina
Diag 10/2006-high grade invasive ductal carcinoma- mastectomy L breast
2.5 cm tumor ER/PR pos-Her2+++
4 rounds A/C, 4 rounds Taxol
Herceptin every 3 weeks until Jan. 2008
6/18/07 prophylatic mastectomy R breast
8/2007 started aromasin/stopped arimidex (side effects)
12/07 stopped aromasin due to side effects (now what?)
Finished herceptin 1/8/08
started tamoxifen for 2 years then will switch to femera
allergic to tamoxifen started femera 4/2008
June 20, 2008 portacath removed
Learnig to live life to the fullest!
Stopped Femera due to side effects
July 28, 2008 start trial for breast cancer vaccine
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07-29-2008, 08:44 AM
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#7
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Senior Member
Join Date: Oct 2005
Location: Boise, Idaho
Posts: 758
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Changed to Aromasin
Well, I took the plunge and changed. There is still pain but not as aggravating as I was having with the Arimidex. I thought I would give it at least 2 or 3 weeks before posting about it. I am glad I switched as what I am experiencing now is much more tolerable.
Love & hugs,
Marlys
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07-29-2008, 11:07 AM
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#8
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Senior Member
Join Date: Jul 2007
Location: Canada
Posts: 2,193
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Hi Marlys
I'm glad the switch to a different AI has made a significant
difference......and it's really nice to see you posting again.
The kids are in the mail, heading back to me!!!
__________________
PinkGirl
Dx Aug/05 at age 51
2cm. Stage 2A, Grade 3
ER+/PR-
Her2 +++
Sept 7/05 Mastectomy
4 FAC, 4 Taxol, no radiation
1 year of Herceptin
Tamoxifen for approx. 4 months,
Arimidex for 5 years
Prophylactic mastectomy June 22/09
" I yam what I yam." - Popeye
My Photo Album
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