Well - here I go again

[IRENE FROM TAMPA]

Just returned from visit with my onc for results from my latest PT scan.

Not what I wanted to hear...

I began Tykerb with Avastin in September after progression on Tykerb/Xeloda. This scan indicated the 2 tumors in my abdom. area have since grown and I now have 2 tumors in my clavial area of my neck. I could feel one for the last couple of weeks and thought / hoping it was a swollen lymph node due to my sinus'. But the scan indicated there are actually two about 1.5 cm. They seemed to have popped up overnite.

Anyway - he wants to start me on Herceptin/Avastin/Taxotere.
I have taken so many drugs in the last 12 years that we are now returning to old ones I have used years ago. I took some Taxotere back in 1999.
We were thinking of using Herceptin/Abraxane/Avastin but decided Taxotere might be better since I was on Abraxane only about 4 years ago.
If this combo does not show some improvement he wants to re-biospy to see if any changes in the cancer.

My tumors have always stayed pretty much in one area and we have managed to keep them in one place so this "distant" move makes me very nervous. I hope we are making the right decision on the choices. I keep thinking why not stay on Tykerb with the other two. We were not sure how I would react with only the Tykerb/Avastin without a chemo added and I guess we got the answer. Does not work for me for long.

I really rely on everyone's experiences on this board so am asking for your input. He just returned from San Antonio and says there is lots out there in the works but not for now. He did mention Pertuzumab but I do not think I would qualify for that trial (I will check it out) He is also concerned with the combo's that he starts me on since I have had so much in the years (although I have always done well).

Thank you all so much.