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Old 12-09-2007, 11:20 PM   #1
harrie
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Trigger finger

I have been starting to experience "trigger finger" in my left thumb. This seems to be happening only at night. I will wake up in the middle of the night and my thumb may be stuck in a bent position. Very strange. I have never experienced this before and from reading about "trigger finger" on the internet, it sounds just like my symptoms.

I am wondering if the heceptin or Arimidex that I am currently taking could be causing this.

Any comments would be appreciated.
Happy holidays everyone!
Harrie
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 12-09-2007, 11:49 PM   #2
Karen W
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Harrie,

It's probably from the Arimidex. I have problems with my fingers getting stuck and I think it is from Aromasin.

Karen
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Old 12-10-2007, 12:06 AM   #3
harrie
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Karen, is Aromasin something similar to Arimidex?

Do you just tolerate the finger situation and stick with the Aromasin?

Also, have you tried anything like ibuprofen to help with the fingers?

Harrie
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 12-10-2007, 03:13 AM   #4
dhealey
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I was on arimidex and had this problem, switched to aromasin. Now fingers cramp alot. There is also femera, these three drugs are vary similar and cause the same side effects. I got a lot of joint pain from both the arimidex and aromasin. Have not tried femera yet. I take advil for the joint pain. Helps some, but doesn't take the pain completely away.
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Debbie in North Carolina
Diag 10/2006-high grade invasive ductal carcinoma- mastectomy L breast
2.5 cm tumor ER/PR pos-Her2+++
4 rounds A/C, 4 rounds Taxol
Herceptin every 3 weeks until Jan. 2008
6/18/07 prophylatic mastectomy R breast
8/2007 started aromasin/stopped arimidex (side effects)
12/07 stopped aromasin due to side effects (now what?)
Finished herceptin 1/8/08
started tamoxifen for 2 years then will switch to femera
allergic to tamoxifen started femera 4/2008
June 20, 2008 portacath removed
Learnig to live life to the fullest!
Stopped Femera due to side effects
July 28, 2008 start trial for breast cancer vaccine
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Old 12-10-2007, 07:24 AM   #5
suzan w
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Cool

When I first started with Herceptin and Arimidex I had terrible joint pain. The pain seemed to move from joint to joint...first was awful hip pain that lasted a few months, then it was the knees, wrists...you get the picture! Interestingly enough the pain subsided to a more manageable level after about 6 months-or maybe I just got used to it??!! Then it hit my thumbs. It was very strange! It was like my thumb joints were frozen. Even now, more than a year after my last herceptin (still on Arimidex) my thumbs give me trouble and it feels like they "lock up". Sorry you are having trouble, but, for me, it is a little bit reassuring when someone else experiences the same weird things that I am! And that is something that I love about this site! My oncologist can look at me quizzically when I mention something like THUMBS, yet here we all understand!!!
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Suzan W.
age 54 at diagnosis
5/05 suspicious mammogram-left breast
5/05 biopsy-invasive lobular carcinoma with LCIS,8mm tumor,stage 1 grade 2, ER+ PR+ Her2+++
6/14/05 bilateral mastectomy, node neg. all scans neg.
Oncotype DX-high risk
8/05-10/05 4 rounds A/C
10/05 -10/06 1 yr. herceptin
arimidex-5 years
2/14/08 started daily self administered injections..FORTEO for severe osteoporosis
7/28/09 BRCA 1 negative BRCA2 POSITIVE
8/17/09 prophylactic salpingo-oophorectomy
10/15/10 last FORTEOinjection
RECLAST infusion(ostoeporosis)
6/14/10 5 year cancerversary!
8/2010-18%increase in bone density!
no further treatments
Oncologist says, "Go do the Happy Dance"
I say,"What a long strange trip its been"
'One day at a time'
6-14-2015. 10 YEAR CANCERVERSARY!
7-16 to 9-16. Extensive (and expensive) dental work done to save teeth. Damage from osteoporosis and chemo and long term bisphosphonate use
6-14-16. 11 YEAR CANCERVERSARY!!
7-20-16 Prolia injection for severe osteoporosis
2 days later, massive hive outbreak. This led to an eventual dx of Chronic Ideopathic Urticaria, an auto-immune disease from HELL.
6-14-17 12 YEAR CANCERVERSARY!!
still suffering from CIU. 4 hospitilizations in the past year

as of today, 10-31-17 in remission from CIU and still, CANCER FREE!!!
6-14-18 13 YEAR CANCERVERSARY!! NED!!
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Old 12-10-2007, 03:50 PM   #6
tricia keegan
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I take arimidex and have this too, someone recommended a cortisone injection into the thumb...painful but effective according to my friend.
Her Dr said it may never come back but there is a chance she will need another injection in the future. It seems to be a regular complaint with arimidex.
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Tricia
Dx July '05 IDC 1.9cm Triple positive 3/9 nodes positive
A/C X 4 ..Taxol/Herceptin x 12 wks then herceptin 1 yr
Rads x 36 ..oophorectomy August '06
Currently taking Arimidex..
June 2011 osteopenia/ zometa x1 yearly- stopped Zometa 2015 as Dexa show normal bone density.
Stopped Arimidex July 2014- Restarted Arimidex 2015 for a further two years on the advice of my Onc.
2014 Normal Dexa scan
2018 Mammo all clear, still NED!
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Old 12-10-2007, 06:40 PM   #7
Jean
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Everyone is different, I know that Becky is taking Arimidex and getting along fine. I stayed on Arminidex and was in strong joint pain, gave it
a full year and the pain was worse. Switched to Femarra and for me
it was 90% better. Slight joint pain now in the am upon rising and once
I get going my joints are fine. A bit stiff but certainly not that pain.

All three do the same job in the estrogen dept. even the pain continues
consider switching.

Hope you feel better!
Hugs,
jean
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Stage 1, Grade 1, 3/30/05
Lumpectomy 4/15/05 - 6MM IDC
Node Neg. (Sentinel node)
ER+ 90% / PR-, Her2+++ by FISH
Ki-67 40%
Arimidex 5/05
Radiation 32 trt, 5/30/05
Oncotype DX test 4/17/06, 31% high risk
TOPO 11 neg. 4/06
Stopped Arimidex 5/06
TCH 5/06, 6 treatments
Herceptin 5/06 - for 1 yr.
9/06 Completed chemo
Started Femara Sept. 2006
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Old 12-10-2007, 07:27 PM   #8
Kimberly Lewis
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I started with Femara and I have had the same symptoms. Right now it is in my left thumb and shooting down the wrist. Ow, been going on for a few months now and thought it was carpel tunnel or something. Interesting to hear that it isn't just me!
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Kim

Diagnosed 7/05
Stage 3a er+(45%) pr+(68%) Her2+ (40%)
3.8 cm + .8cm multi focal - pleomorphic lobular tumors
high grade DCIS
7/20 nodes

BRCA 2
positive as of 5/07
surgeries: double mastectomy, hysterectomy (LAVH)
A/C,Herceptin for 1 year completed 11/06
femara


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Old 12-10-2007, 09:29 PM   #9
Karen W
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Harrie,

Yes, Aromasin is an aromatase inhibitor just like Arimidex.

To be able to tolerate the sticky finger situation, I take 4oz of the brazilian acai berry, which is high in omega 3, epa -dha omega 3 and inflavonoid, which is turmeric. All of these supplements are anti-inflammatory and really do help. There are days though, that nothing helps and then I need a good dose of ibuprofin.

Karen
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Old 12-10-2007, 09:40 PM   #10
hutchibk
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I had really stiff fingers on Herceptin and Aromasin. Since I stopped both of those it has gone away.
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Brenda

NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)

Nov'03~ dX stage 2B
Dec'03~
Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~
Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~
micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~
micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg

Apr'07~
MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~
Started Tykerb/Xeloda, no WBR for now
June'07~
MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~
MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~
PET/CT & MRI show NED
Apr'08~
scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~
MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~
dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~
Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~
new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~
new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~
25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.

"I would rather be anecdotally alive than statistically dead."
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Old 12-10-2007, 11:24 PM   #11
harrie
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Thank you everyone for your input. I really appreciate it. I absolutely love this online site and really do not know what I would do without it. It feels so funny being able to share so much personal information and get such honest feedback with so many wonderful people that I have never personally met. I thank you all.

I will bear with this thumb situation for now and hope it does not get worse. I am a dental hygienist and I do need my hands to function adequately. It feels so strange when the thumb locks and then it kinda like pops back into normal position. During the day (so far) it does not do this, but it may feel a bit weak and slightly tender upon palpation of the lower portion of the thumb area, palm side.

Happy holidays to all of you.
I plan to celebrate to the fullest this year, gratelful to enjoy the holidays in great health and spirits.

Hugs,
Harrie
__________________
*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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Old 12-11-2007, 09:34 AM   #12
Hopeful
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Harrie,

I do not have "trigger finger" (yet!) but a lot of hand joint pain on Arimidex. I was looking at the John Hopkins' website, and, apparently, there are a number of patients on Arimidex/Aromasin with a similar problem submitting questions. Lillian Shockley, who answers the questions, said that she has told all of the AI drug companies about the high number of questions she is receiving about this symptom. Just wanted to let everyone know that this is not an unusual side effect. The only way we will get proper medical attention for it is to continue to speak up to our doctors and the drug companies. Thanks for posting this question here.

FYI, here is a link to the Mayo Clinic Website with more info on trigger finger: http://www.mayoclinic.com/health/trigger-finger/DS00155

Hopeful
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Old 12-11-2007, 11:45 PM   #13
harrie
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I hope I am not speaking a bit to prematurely, BUT....last night I rubbed some Traumeel which is a homeopathic gel that is anti-inflammatory and analgesic on the base of my thumb area plus I took one Advil and I noticed my thumb was not as bad as previous nights.

Going to try that again tonight.

Harrie
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*** MARYANNE *** aka HARRIECANARIE

1993: right side DCIS, lumpectomy, rads
1999: left side DCIS, lumpectomy, rads, tamoxifen

2006:
BRCA 2 positive
Stage I, invasive DCIS (6mm x 5mm)
Grade: intermediate
sentinal node biopsy: neg
HER2/neu amplified 4.7
ER+/PR+
TOPO II neg
Oncotype dx 20
Bilat mastectomy with DIEP flap reconstruction
oophorectomy

2007:
6 cycles TCH (taxotere, carboplatin, herceptin)
finished 1 yr herceptin 05/07
Arimidex, stopped after almost 1 yr
Femara
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