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Old 07-23-2007, 07:28 AM   #1
Hopeful
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Blc2 is a prognosticator for IDC

The article: http://www.breastcancersource.com/br..._27859___.aspx

The abstract: http://annonc.oxfordjournals.org/cgi...ract/18/6/1004

Of interest:

"Results: In the entire series, the Bcl2 variable was an independent<SUP> </SUP>predictor of clinical outcome, and its prognostic independence<SUP> </SUP>was maintained when lymph node-negative and -positive patients<SUP> </SUP>were considered separately. In this regard, of particular interest<SUP> </SUP>was the observation of a subgroup of node-negative breast cancer<SUP> </SUP>patients with a negative Bcl2 immunostaining, who had a very<SUP> </SUP>high probability of relapse or death (respectively about five<SUP> </SUP>and seven times greater than patients with a positive Bcl2 immunostaining).<SUP> </SUP>Moreover, the Bcl2 variable retained prognostic significance<SUP> </SUP>also in subgroups of patients treated with either adjuvant endocrine<SUP> </SUP>therapy or chemotherapy.<SUP>"</SUP>
<SUP></SUP>
<SUP></SUP>
<SUP>Hopeful</SUP>
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Old 07-23-2007, 07:36 AM   #2
Mary Jo
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Location: Sheboygan, WI
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Thanks for posting this Hopeful. As most of the articles posted here I don't understand most of them really and have no idea how I would find out half the stuff mentioned in them as it pertains to my particular cancer BUT this article caused me to chuckle anyway. There was a quote by a "team" from the "University of Bologna." LOL LOL LOL! I got a kick out of that.

Have a great day and thanks to everyone who stays on top of this world called breast cancer. You are a blessing to all of us.

Mary Jo
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"Be still and know that I am God." Psalm 46:10

Dx. 6/24/05 age 45 Right Breast IDC
ER/PR. Neg., - Her2+++
RB Mast. - 7/28/05 - 4 cm. tumor
Margins clear - 1 microscopic cell 1 sent. node
No Vasucular Invasion
4 DD A/C - 4 DD Taxol & Herceptin
1 full year of Herceptin received every 3 weeks
28 rads
prophylactic Mast. 3/2/06

17 Years NED

<>< Romans 8:28
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Old 07-23-2007, 09:06 PM   #3
jhandley
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Smile Q 10

Co-enzyme Q10 restores the bcl 2 gene to its normal fuction. Search under bcl-2 and Q10.
cheers
jackie
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