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03-09-2007, 09:46 AM
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#1
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Senior Member
Join Date: Oct 2006
Location: Louisville KY
Naples FL
Posts: 665
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Herceptin and Antibiotics
Hi all
Just a question for the experts. I came down with a sore throat and cold last
week and the Dr. gave me antibiotics for 10 days. My herceptin treatment is
next Wednesday, I don't want to miss it but should I reshedule it after the antibiotics. My cold is better but I guess I shouldn't stop the antibiotics.
There are so many meds that don't work well together, and when I read the
insert I thought antibiotics are dangerous too. When you are taking so many
drugs, its hard to keep up with all the side effects.
patb
Thanks
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03-09-2007, 10:59 AM
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#2
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Senior Member
Join Date: May 2006
Posts: 93
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Just be sure to mention what you are taking when you go in to get your infusion. Your infusion RN should check with your oncologist if she has any questions.
According to the prescribing information for herceptin, there have been no controlled drug interaction studies. http://www.gene.com/gene/products/in...traindications
__________________
Husband to Jill
Diagnosed 10/05, age 39
R Mast 11/05
Stage II N0
Her2+ er/pr+
Revision Mast due to positive margins 12/05
TCH Chemo started 1/06
Finished TC 4/06
Tamoxifen
Finished H 12/29/06
Currently NED
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03-09-2007, 12:02 PM
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#3
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Senior Member
Join Date: Sep 2005
Location: Stockton, NJ
Posts: 4,179
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I was on Cipro, Augmentin or Macrobid 100 for recurring UTIs while on Herceptin. I know these drugs were ok.
Just an fyi
__________________
Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
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03-09-2007, 12:05 PM
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#4
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Senior Member
Join Date: Sep 2005
Location: Grand Rapids, MI
Posts: 1,516
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Gina...
has said that Z pack (Zithromyacin) actually may HELP reduce the level of HER2 in our body. I am trying to find one of her posts regarding. Ask your doc if you can get a Z pack as this is what I have taken when needed.
Rhonda
http://her2support.org/vbulletin/sho...hromyacin+gina
__________________
Rhonda
Dx 2/1/05, Stage 1, 0 nodes, Grade 3, ER/PR-, HER2+ (3.16 Fish)
2/7/05, Partial Mastectomy
5/18/05 Finished 6 rounds of dose dense TEC (Taxotere, Epirubicin and Cytoxan)
8/1/05 Finished 33 rads
8/18/05 Started Herceptin, every 3 weeks for a year (last one 8/10/06)
2/1/13...8 year Cancerversary and I am "perfect" (at least where cancer is concerned;)
" And in the end, it's not the years in your life that count. It's the life in your years."- Abraham Lincoln
Last edited by RhondaH; 03-09-2007 at 12:06 PM..
Reason: addition
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03-09-2007, 04:09 PM
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#5
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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Pat B,
Since I started Herceptin last June I've had numerous sinus infections - have one right now. I've been on and off Levaquin several times and currently am taking Avelox along with prednisone (spelling?) a steroid to reduce the swelling in the sinus. I have not had to miss a Herceptin treatment while on anticiotics. My oncologist is the one who prescribed the antibiotics to me so she is aware that I'm taking them. Hopefully, once I finish Herceptin I will no longer be plagued with sinus infections.
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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03-09-2007, 05:32 PM
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#6
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Senior Member
Join Date: Aug 2006
Location: Franklin, MA
Posts: 131
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Had a Herceptin Treatment Today...
...and am on the 3rd day of the Z-pack. I have also been plagued by sinus infections this winter and have never had a break in my treatments (Navelbine/Herceptin/Zometa) due to being on Antibiotics (I have been on amoxicillin, cipro and leviquin). You should always mention any new prescriptions prescribed by your primary care doctor when you go for chemo, but I don't think it will stop your treatment. The one thing you should be aware of is that if you normally take any antacid type medications for queasiness after chemo, the antacids impact the effectiveness of the antibiotics.
__________________
Diagnosed 10-03-2005 (34 wks pregnant, 38 yrs old)
Lumpectomy Nov-2005. 10/18 Lymph Nodes impacted
Mets to liver, spine & femurs (thus being stage IV right from the get-go)
ER-, PR-, HER2+
Taxol/Herceptin/Zometa started Dec-2005. 11 cycles of Taxol.
Sept-2006: PET/CT scan of mets to liver, spine and femurs - Stable. Activity in R breast & mediastinum (not seen in prior scans).
Navelbine (3 wks on/1 wk off) as of Oct--2006 & continued Herceptin (every 3 wks) & Zometa (every 6 wks)
Jan-2007: PET/CT Scan - Stable. Continued Nav. through March-2007, then Herc./Zom. only after that.
June-2007: PET/CT Scan - activity in mediastinum. Back on Navelbine as of July-2007.
Scanned Quarterly since Oct-2007 - a few small scares, but otherwise stable due to continuing weekly Navelbine, Herceptin and Quarterly Zometa.
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03-09-2007, 06:34 PM
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#7
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Senior Member
Join Date: Sep 2005
Location: Mountains of Virginia
Posts: 2,267
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I was on some type of antibiotic almost the entire time I was on Herceptin. From z-pack for sinus infection to the big guns for staph infection. Evidently no adverse effects from the antibiotics.
________
Vaporizer
Last edited by sassy; 08-22-2011 at 09:10 AM..
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03-09-2007, 06:39 PM
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#8
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Senior Member
Join Date: Aug 2001
Location: Oregon
Posts: 1,756
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I just came off a 10 day course of Levaquin (2 five day courses, back-to-back) for a bad cold, to prevent developing pneumonia while on Herceptin/Gemzar. No complications related to the antibiotic.
<3 Lolly
__________________
Sept.'99 - Dx.Stage IIIB, IDC ER/PR-, HER2+++ by IHC, confirmed '04 by FISH. Left MRM, AC x's 4, Taxol x's 4, 33 Rads, finishing Tx May 2000. Jan.'01 - local/regional recurrence, Stage IV. Herceptin/Navelbine weekly till NED August 2001, then maintenance Herceptin. Right Mast. April 2002. Local/Regional recurrence April '04, Herceptin plus/minus chemo until May '07. Gemzar added from Feb.'07-April '07; Tykerb/Abraxane until August '07, back on Herceptin plus Taxotere and Xeloda Sept. '07. Stopped T/X Nov. '07, stopped Herceptin Dec. '07, started Avastin/Taxol/Carboplatin Dec. '07. Progression in chest skin, stopped TAC March '03, started radiation.
Herceptin has served as the "Backbone" of my treatment strategy for over 6 years, giving me great quality of life. In 2005, I was privileged to participate in the University of Washington/Seattle HER2 Vaccine Trial.
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