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Old 01-28-2007, 05:59 AM   #1
VirginiaGirl
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Location: Fredericksburg, VA
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Scheduling scans during treatment?

I'm due for a PET/CT combo scan to evaluate my response to Taxotere/Herceptin and when I called to schedule they said I have to be three weeks out from my last treatment (I'm on a three-week schedule). Has anyone else run into this and what would the reason be? I see my onc Monday and will ask then, but was curious to hear any feedback from others. Thanks!
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Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin

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Old 01-28-2007, 10:29 AM   #2
Colleen007
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I got my first PET/CT scan on September. My Oncologist actually wanted me to wait 8 - 12 weeks after I stopped Taxol at the end of June because she said that the chemo drugs sometimes create inaccurate readings on the scans. When I had my next PET scan earlier this month (while on Navelbine), I didn't have to wait so long because they already had the September baseline which gave them a good read on spots that were just "physiological uptake" vs. cancerous uptake.

Good luck!
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Diagnosed 10-03-2005 (34 wks pregnant, 38 yrs old)
Lumpectomy Nov-2005. 10/18 Lymph Nodes impacted
Mets to liver, spine & femurs (thus being stage IV right from the get-go)
ER-, PR-, HER2+
Taxol/Herceptin/Zometa started Dec-2005. 11 cycles of Taxol.
Sept-2006: PET/CT scan of mets to liver, spine and femurs - Stable. Activity in R breast & mediastinum (not seen in prior scans).
Navelbine (3 wks on/1 wk off) as of Oct--2006 & continued Herceptin (every 3 wks) & Zometa (every 6 wks)
Jan-2007: PET/CT Scan - Stable. Continued Nav. through March-2007, then Herc./Zom. only after that.
June-2007: PET/CT Scan - activity in mediastinum. Back on Navelbine as of July-2007.
Scanned Quarterly since Oct-2007 - a few small scares, but otherwise stable due to continuing weekly Navelbine, Herceptin and Quarterly Zometa.
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Old 01-28-2007, 12:39 PM   #3
tousled1
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I get PET/CT scans every about every three months. I'm on Herceptin only and I've never had any problems.
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Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 01-28-2007, 02:36 PM   #4
Chelee
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I was doing TCH, (Taxotere, Carbo & Herceptin) and I was never told to wait. In fact once my onc had set-up my PET/CT for the 3rd day after my chemo when I would feel my worse. I told her I could not do that. She let me re-schedule for the following week. I did notice that PET/CT report did mention things that showed up but it would say something like, "increased uptake in bone marrow consistent with chemotherapy".

My first PET/CT was BEFORE I started chemo...the 2nd was was DURING...and my last one was 5 months after my last chemo.

Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
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Old 01-28-2007, 04:39 PM   #5
doh2pa
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Hi Liz,

I, too, am on a three week chemo schedule. I usually have my scans on the week before my chemo (so it's the second week out). Have never had any problems or weird results.

Donna
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Donna
Diagnosed 2/04 - Invasive ductal - no clean margins
node negative - er+pr+, her2++
Mastectomy 4/04 - 4 rounds AC
9/05 - mets to liver treated with carbo/ixabipelone/herceptin
3/06 - complete remission
9/06 - new liver mets, starting Taxotere/Herceptin
1/07 -Liver mets stable, staying on Herceptin
5/07 - Liver, lung progression - starting T/X
12/07 - Liver, lung progression - starting weekly Navilbene/Herceptin
4/08 - Liver progression - started Abraxane, Carbo, Tykerb and Herceptin
7/08 - Liver Progression - started Gemzar, Avastin and Tykerb
10/08 - Liver progression - starting Doxil
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Old 01-28-2007, 04:51 PM   #6
Sherryg683
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I had scans done every 6 weeks while on chemo, the way it would fall is that my scans would be right before I would start the taxotere treatment which I did every 3 weeks...I don't think it mattered though.....sherryg683
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Sherry

Diagnosed: December , 2005 at age 44
13+ positive lymph nodes
Stage IV , Her2+, 2 small mets to lungsChemo Started: Jan, 2006
4 months Taxotere, Xeloda, Hercepin
NED since April 2006!!
36 Rads to follow with weekly Herceptin indefinately
8 years NED now
Scans every year

Life is not about avoiding the thunderstorms, it's about learning to dance in the rain!
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Old 01-28-2007, 07:59 PM   #7
caya
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Hello All,


I am fairly new to the site. I was diagnosed in October 2006, due to plastic surgeon finding a tumor while doing my breast reduction surgery. So began the rounds of all the scans - transvaginal ultrasound, liver ultrasound, bone scan, bloodwork, CT of the brain, chest X-ray, MRI of the left breast - all clear. Had a mastectomy (right) on Dec. 18th, all 16 lymph nodes tested were clear. Original tumor (found during breast reduction) was 1.7 cm, ER+PR+ HER 2+++ (FISH) stage 1, grade 1. They found another tumor during the mastectomy - 1.0 cm., stage 1, grade 2 did not test for ER,PR, HER2 because of the previous tumor. I started FEC-T this past Thursday ( once every 3 weeks for 6 rounds ), then will be on Herceptin for a year ( once every 3 weeks). My question is - how often should I be getting the scans - especially bone and brain - I haven't had a brain MRI - just a CT, which was clear. Any advise from the veterans would be much appreciated!!

Thanks
Caya
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Old 01-29-2007, 07:50 AM   #8
Lee
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Join Date: Jan 2006
Posts: 58
I had scans while undergoing chemo....

....and I was getting chemo weekly. It was never an issue. My onc wanted to be sure the chemo was working, and the only way to check that is to do scans.

Can you have your onc's office call to schedule the appointment? They always do my scheduling.
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Old 01-30-2007, 03:56 PM   #9
VirginiaGirl
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Join Date: Oct 2006
Location: Fredericksburg, VA
Posts: 93
Thanks to everyone for replying! When I asked the nurse at my onc's office, she said it was to give the chemo drugs time to get out of my system to keep the readings more accurate. It just surprised me because when I had the last PET/CT in Nov. I was only doing Herceptin and nothing had been said either way.

Cara - there are a few recent links about the whole brain MRI scanning issue you asked about, I think if you use the search link above it will find them, but more experienced users feel free to correct me/provide better guidance!

Peace and Blessings,
__________________
Liz
3/05 Initial dx invasive dc 2 cm lump, age 39
lumpectomy & 3 of 5 nodes +, ER+/PR+, Her2+++
alternative chemo 5/05-7/05, rad 8/05-10/05
7/06 dx mets to vertebrae, pelvis & chest lymph nodes
8/06 - 10/06 tamoxifen, herceptin, oophorectomy & zometa
11/06 PET/CT showed continued bone mets, new spot on liver
12/06 began taxotere/herceptin 1x/3 weeks,
2/07 - 2-08 NED!
3/08 progression, start taxol/herceptin weekly, monthly zometa
8/08 start ai & herceptin
12/08 - progression, start weekly navelbine/herceptin thru 6/09 & monthly zometa
7/09 - PET/CT showed improvement in spine, but 2-3 lymph nodes in chest became active
9/09 - 11/09 - weekly abraxane/herceptin
12/09 - PET/CT - chest lymph nodes resolved, progression in spine & pelvis
2/10 - 6/10 - start tykerb/xeloda, progession in spine & pelvis
7/10 - start taxotere/carboplatin/herceptin

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