numbers

[Joy]

Hi everyone, I hate to bring this up again, but there is no better place to discuss these things. So, I'm on Navlebine/Herceptin and as you may remember I had great response in the very beginning (September). Now, I'm not so sure if that is still true. I have scans on the 22nd, but I can't help myself in obessessing about some numbers. My December CA 27.29 was 143-the lowest since the Fall. My January result is 163. Also my ALT/AST are holding steady at a little above normal prior to Navelbine they were fairly elevated. I've been watching my bilirubin and alkaline phosphase on my chem panels and the bilirubin seems fine (always something to be grateful for). My alk phos has been steadily rising within the normal range. In the last few month it has gone 103, 115, 103, 113, 125 and now 150 (which per my lab is the highest normal value).

To add to my worry, or maybe because of it, I am having a lot of digestive problems. I have had them moderately for the last year during good tests and bad. They just seem to get worse. I kind of feel like I have IBS. I realized today at treatment that kytril and navelbine are both constipating and that has been an issue and it seems logical that that is some of the problem.

My worries are:
- The navelbine is no longer working I'm sure herceptin doesn't do much for me after 41/2 years.
-Are the alk phos results indicative of liver function problems, especially when backed up (pardon the pun) to the digestive problems.
-I have lots of little transient pains all over my abdomen (I know I am over focused on it too).
-Is Navlebine cumulatively harder on the liver?
-If this treatment is failing will the next one fail as fast?
-Am I becoming too heavily pre-treated now that this is my 3rd line of tx for MBC?
-Is Tykerb really going to be available next month? Or, should I go through the hassle of getting on the EAP?

Anybody's thoughts or ideas or experiences would be so very appreciated!!!

Thanks for being there.