the good news about etag

[Lani]

saw Rhonda's post in articles about etag and investigated further...the good news is that it can be performed on FFPE ie, formalin-fixed, paraffin-embedded tumor samples ie, no fresh-frozen tumor necessary is true for multigene arrays.

If this pans out, the typical specimens still lying in the hospitals' pathology departments can be investigated to help patient decide which therapies are likely to help, particularly targetted therapies.

Individual tailored treatment for tumors although still far away is coming closer...:

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How eTag Assays Work

eTag™ assay technology measures stable protein complexes in standard tissue sample formats from patients, providing the user with decision-critical knowledge of activated signaling pathways.



eTag assays enable the analysis of very small quantities of tumor cells recovered and prepared using various methods, including formalin-fixed, paraffin-embedded (FFPE) samples, the current standard in hospital pathology laboratories:
eTag technology is standard across different assays/analytes

eTag assays enable characterization of a disease at the molecular level, providing, accurate, quantitative measurements

eTag assays can detect specific protein complexes, especially receptor complexes, which initiate many signal transduction cascades in cells and are the targets for many of the newer cancer therapies

eTag assays can accurately predict a patient's response to a given therapy, facilitating the selection of more precise and effective therapeutic options