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Old 04-13-2006, 05:02 AM   #1
IRENE FROM TAMPA
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Location: TAMPA, FL
Posts: 568
question regarding Tykerb

Did I understand correctly that it might be possible to start on Tykerb before it is actually approved by FDA?

I have progression in my tumor and I have some decisions to make soon and if above possible, would love to take that route.

If this is so, what has to be done?

would appreciate any input

Thanks to all
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Irene from Tampa
1996 - INFILT DUCTAL CAR.W/ LYMPH NODE INVOLVEMENT. ADRIA/CYTOXIN/5FU
1999 - RECURR. TO AUXILA AND 2 TUMORS IN LIVER
TREAT: STEM CELL REPLACEMENT/HERCEPTIN.
2002 - RECUR TO LIVER
TREAT: NAVELBINE, THEN GEMZAR, THEN XELODA.
2004 - TUMORS STILL IN LIVER
TREAT: RFA TO LIVER
STABLE UNTIL
2004 - TUMOR PROGRESSION IN LIVER.
TREAT: RESECT HALF OF LIVER.
2005 - RECURR TO LYMPH NODE OUTSIDE OF LIVER.
TREAT: TAXOL/CARPO/HERCEPTIN. FAILED ON
THIS TRIO. STARTED ON ABRAXANE.
2006 - PROGRESS WITH 2ND TUMOR GROWTH.
TREAT: AUG. BEGAN ON TYKERB/XELODA
TRIAL. CONSIDERED STABLE TO DATE.
2007 - TAKEN OFF OF TYKERB/XELODA TRIAL DUE TO
PROGRESS STARTING TYKERB/AVASTIN.
NOV 2007 - SCANS SHOW PROGRESS TUMOR GROWTH
IN ABDOM. AND TWO NEW TUMORS IN NECK AREA.
BEGAN HERCEPTIN/AVASTIN/TAXOTERE
Feb 08 - Ixempra/Xeloda
June 08 - Her/DM1 trial

"I WANT TO BE AN OUTRAGEOUS OLD WOMAN WHO NEVER GETS CALLED AN OLD LADY. I WANT TO GET SHARP EDGED & EARTH COLORED, TILL I FADE AWAY FROM PURE JOY."
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Old 04-13-2006, 06:58 AM   #2
Cathya
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Location: Ontario, Canada
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Irene;

Joe posted the information I am pasting below. I signed up for a study and received a response within one day and spoke to the woman who is the co-ordinator in an area near me. I would give it a try. Best of luck and keep us posted. Cathy

TYKERB - Clinical Trial
We previously sent you an e-mail about three (3) breast cancer clinical research studies (clinical trials) being conducted in your area that may be of interest to you. The studies are evaluating the safety and effectiveness of an investigational oral drug, GW572016, for the treatment of advanced or metastatic, Stage III or IV, breast cancer in women. If you have already called about these clinical trials, there is no need to call again. However, if you have not called, we wanted to give you another opportunity to participate in these clinical trials.

Below are some of the criteria that you must meet to be eligible for this study:
  • Female, at least 18 years of age
  • Diagnosed with Stage III or Stage IV breast cancer
  • Able to swallow and retain oral medications
  • Not currently pregnant or nursing.
Additional criteria will be evaluated to determine your eligibility.

All qualified study participants will receive the investigational drug at no cost. The length of study participation is dependent on how each woman and her tumor(s) respond to the study drug(s).

If these studies interest you and you wish to find out if you may be eligible to participate, we invite you to contact Acurian for pre-screening by clicking here or calling toll free 1-800-563-6118.

About Acurian
Acurian is a company that specializes in education and awareness campaigns for clinical research studies. They are working with the sponsor of these studies to coordinate the pre-screening and referral of women to the research sites for further evaluation and consideration for participation in these breast cancer research studies.

Acurian's Privacy Statement:
Your responses to the pre-screening questions will be kept confidential and will only be shared with the research study doctor's staff to help them determine your final eligibility for this study. This de-identified data may also be shared with the study sponsor, and its representatives, should you be enrolled. Your information will be saved at Acurian only until the study is complete; then it will be destroyed. The decision to participate will be yours alone and you can change your mind at any time.

To see if you are eligible and get more information on the clinical trials, click here
http://www.cancerprofiler.nexcura.com/go/acurianbreast
or call toll-free 1-800-563-6118.

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Old 04-13-2006, 07:59 AM   #3
Shell
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Irene-


I am kgetting tykerb, but as part of a clinical trial - below in the other posts about this you will note posts that will let you see if tykerb is available to others outside of that trial...
good luck,
shell
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