***Calling all Stage 1, node neg, ER+/PR-, HER2+ girls***

RhondaH · 03-10-2006, 02:03 PM

I am trying to help someone w/ this pathology and was wondering if you could tell me your dx as well as your treatment? I know there is info on this, but when I do a search, I come up w/ EVERYTHING. Thank you.

Rhonda

karenann · 03-10-2006, 03:02 PM

Hi Rhonda,

I was diagnosed with: stage one, node negative, er+ 95% and pr+10%, 1.3cm tumor and Her2+++. I did 4 dose dense AC and then 4 dose dense T (taxol), 34 rads (5 were a boost), one year of Herceptin, started 2 weeks after my last Taxol and Aromasin for 5 years and I will have my ovaries removed in July. Oh, I had a lumpectomy.

Hope this helps.

Karen

Maggie · 03-10-2006, 03:52 PM

Hello Rhonda,

I was stage 1, 1.2 cm, node negative, ER/PR neg. HER2 +++ strong.
I had ACx4 and 33 rads. I finished treatment 12/23/04, but chemo was finished end of September.
When I found out they would probably approve herceptin for early stage BC in November, I was ready to jump on the wagon. My oncologist had me tested for HER2/neu by FISH and It came back plus, so I was ready to start herceptin, 13 months after chemo.
Hope this is helpful! BTW... I had a lumpectomy! Clean margins!

Maggie

CherylS · 03-10-2006, 04:01 PM

Rhonda,

I was dx stage 1, node neg., 1.7 cm tumor, grade 3, ER + 75%, PR -, HER2 +++.
I had lumpectomy first, 4 AC, 12 weekly Taxol with Herceptin and Herceptin continued for 1 year. No radiation because I later opted for bi-lateral masectomy, otherwise I would have had rads too. I also had my ovaries out because I was premenopausal and wanted to be able to take Aromtase Inhibitor.
I just had to do everything I could to prevent going through this again.

Best wishes to your friend.

03-10-2006, 04:37 PM

Hi,

I was stage I, ER/PR-, Her2+++, no nodes. I had a bilateral mastectomy. 4 a/c, 4 taxol, dose dense. 1 year of Herceptin. No rads.

Olivia

Marlys · 03-10-2006, 04:55 PM

Rhonda,
I am stage 1,IDC high grade tumor, DCIS, ER+++, P+, HER2+++, Sentinel node negative, , lumpectomy x 2 to get clear margins, AC x 4, Rads x 30, Herceptin every 3 weeks for 1 year started July 19,2005. Marlys
P.S. Don't stay away!!!

CLTann · 03-10-2006, 06:53 PM

I am 61 years old. ER, PR and Her2 all positive. Tumor 0.8 cm invasive ductal cancer. Opted for mastectomy. No chemo. No radiation. Margin clear. No node involvement. On arimidex. well differentiated grade 2 cancer cells. Cancer discovered and removed 09/05. So far, so good.

Ann

Jade · 03-11-2006, 12:06 AM

Dx @ 49 yrs. old, 11/04, Stage I, Grade III/3, 8mm tumour, ER/PR-/HER2+++, node negative, simple mastectomy 11/04, started chemo 2/05, 4 rounds Epirubicin & Cyclophosphamide (EC) every 3 weeks, started Herceptin Aug/05 every 3 weeks for a year.
I lurked about on the site for a few months before joining; was reluctant as I felt like such a wimp compared to some of the incredibly brave and courageous women here. You are truly warriors and are an amazing source of information and strength.
Thank you!
P.S. Hi, I just noted you were looking for info on dx with ER+ which I'm not - sorry!

DeborahNC · 03-11-2006, 07:18 AM

Rhonda,

Thanks for showing interest in us Stage 1's. At times I get the feeling Stage 1 is not considered a genuine 'cancer experience'.

I am Stage 1, .3cm IDC (extensive DCIS), Er+ (weakly)/PR-, Grade 2, node neg via SNL, Her+++, post bi. mastectomy. Rec. tx. 6 rounds Taxol/Herceptin; I only got through 3 rounds Taxol due to severe neuropathy. Will continue with one year Herceptin.

Two years prior to this ocurrance I was Stage 0; lumpectomy with 33 rads.

edit: I'm 52, Taxol pushed me finally into menopause. All the best to your friend and I'm glad to see you posting.

Valerie · 03-12-2006, 09:33 PM

Hi Rhonda,
I was diagnosed at age 49 in Feb 2004.
Stage 1 .4mm tumor, weak er+, pr indeterminate, her2+++,
grade 3 . Sentinel node negative. I had a lumpectomy in April 2004, 4 rounds of AC. Radiation finished in Oct. 2004.
I started herceptin in Nov. 2005. I also had my ovaries out due to ovarian cysts in Dec. 2004. So far herceptin has been ok.
Valerie

jsattaw · 03-12-2006, 10:02 PM

Hi Rhonda --

I was first dx in '98 -- stage 1, ER+ PR+ but didn't know HEr2 status then. I had a lumpectomy with radiation. I recurred in May '05, did a mast with reconstruction (still node negative) although I had multi-centric IDC. The path was the same as the first -- but also HER2+. My sentinel node biopsy was negative. I did 4 taxol treatments and then started Herceptin every 3 weeks. I also did a complete hysterectomy and am now on Arimedex.

Best wishes for your friend!

Jill

AlaskaAngel · 03-13-2006, 12:08 PM

Hi Rhonda,

Dx at age 50 in 2001, treatment in 2002 with SNB, lumpectomy, rads, tamoxifen, Arimidex for 1.6 cm IDC node-negative HER2+++, ER+, PR+. Thanks for the question.

A.A.

03-13-2006, 12:48 PM

I was dx in april 05, er.pr and her2 ++. had a lumpectomy, 4 rounds of AC/ then 12 weekly taxol and herceptin, then 33 rads, and herceptin for a year.

No node involvement. All i have left is about 8 tx of herceptin and I'm done
wahooooooooooo

Michelle · 03-13-2006, 05:30 PM

I was dxed in March of 2005-stage1c, 1.9cm, er+ 90%, and borderline pr, her2+++. My treatment was 4 AC, 4 taxol, 36 rads, tamoxifen, and continueing herceptin. Best wishes on your friends treatment.
Michelle

sadie · 03-13-2006, 08:07 PM

HI Rhonda,
I was dx Oct 2005 at age 51 post menapausal.
Stage 1 / 1cm / Sentinel node neg / er+ / weakly pr+ /her2+++ / grade 3
Had lumpectomy; 4 rounds AC; Now getting Taxol w/Herceptin 1/week for 12 weeks; Then 30 days radiation; Will continue Herceptin every 3 weeks for 1 year total Herceptin; Will be getting armidex.

MCS · 03-14-2006, 08:00 PM

50 years old
dx in sept 05
mastectomy right breast
1cm
node positive
her2+
er neg, pr neg
4 ac
4 taxol w herceptin
currently on herceptin
no radiation

MCS (Maria)

BEVIE · 03-14-2006, 10:27 PM

Hi Rhonda,

I was dx 10/2000 at 49 yrs old, stage 1, node neg.,1.5 cm tumor, grade 2, ER strongly + PR+ Her++ I had lumpectomy, 4 AC, 28 rads. Tamoxifen 9 months Arimidex 3 1/2 yrs. so far so good.
Hope this helps.
Bevie

03-15-2006, 05:35 AM

good morning
I was diagnosed infiltrating ductal carcinoma 1/2004 stage 1
e and p positive
her2 positive (2+)
had lumpectomy radiation and now arimidex
I did not have chemo or herceptin
should I ask aout herceptin now

katcdale@yahoo.com · 03-24-2006, 12:25 PM

Why are you having your ovaries taken out?? I had a hysterec., but still have my ovaries. What test do you take to see if the C has spread to your ovaries??

katcdale@yahoo.com · 03-24-2006, 12:36 PM

There are 2 tests to see if you have the HER2 protein--ICH and the F.I.S.H. the F.I.S.H. is the more accurate of the two. The ICH is rated 1+,2+. and 3+ depending on the amount of staining and how heavily your biops. tissue was stained. It is looked at by human eyes. My ICH test was 3+.
The F.I.S.H. is the more accurate one, but doctors say it is very expensive. Since the ICH can have a 2% false positive reading, I demanded the FISH test which also came out positive. I did not want to take the Herceptin unless I knew it could help me for sure. Kat in the delta