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Old 01-29-2006, 05:00 PM   #1
al from Canada
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Join Date: Jul 2005
Location: Ontario, Canada
Posts: 722
finally, someone tells the HER2 survival story the way it is:

What we suspected all along is confirmed for the first time I'm aware of in print:

"These data suggest that trastuzumab radically changes the natural history of HER2-positive metastatic breast cancer. While women with HER2-positive tumors have historically been thought to have a worse prognosis, the advent of trastuzumab means that they appear to do far better in response to chemotherapy than do patients with HER2-negative tumors, exhibiting higher rates of response, longer durations of treatment, and improved overall survival. Thus, HER2-negative and HER2-positive tumors remain clinically distinct, and it is not fair to say that HER2-negative outcomes are equivalent to HER2-positive outcomes in patients also receiving trastuzumab."

For those who want to read the whole article:
http://www.medscape.com/viewarticle/466393

Finally, we're out of the dungeon; kind of like the tortoise and the rabbit wouldn't you say?

Regards,
Al
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