Calling All Lung Mets Survivors!

[Lolly]

Hello Friends; My Her2+++ friend has had a 2nd recurrence of lung mets, after over 2 years of NED on maintenance Herceptin. I am hoping those of you who've dealt with lung mets will post your treatment regimens and response so she will have some ideas to go on when she meets with her oncologist Tuesday. I will print out your responsed for her to read. Thank you for any help!

Love, Lolly

Hi Lolly,

I' have mets to lungs and liver. Been on clinical trial of avastin and taxol for one year now. Lungs are in remission (since April) and liver lesions are less and smaller...now stable. Don't know if it's the taxol, avastin or both. Avastin is being used in many trials. It is approved for colon cancer...not bc yet...hope this helps

Warmly,

judiek

History

Discovered lump Sept. 2002 (mammo didn’t pick it up)
Dx Oct 2002-just turned 41
IDC and pagets disease, stage 2B, grade 3/3, nottingham scale 9/9
3cm, lumpectomy,clean margins
er/pr-pos, her2 neg, 2/25 nodes w/cancer
Nov 2002-March 2003-FEC (5fu, epirubicin, cytoxen)
March 2003- started tamoxifen
May 2003- finished rads (33tx)
June 2003-CT/PET Scan- clear
Started 3 month check ups w/lab
Dec 2003-complete hysterectomy
Jan 2004-extensive mets, both lungs & liver(labs normal)
Jan -stopped tamoxifen
Feb CEA-23 (0-3 normal) CA27.29-66.1 (0-38 normal)
Feb 23to current-clinical trial, taxol & avastin
April 15th, -CT-significant shrinkage on all tumors/plueral effusion gone
June 8th -CT-all liver lesions decreased in size/lung mets gone
Aug 9th, -CA27.29 is 22.3, CEA is .8)
Aug 9th, 2004-Brain-CT neg, lung mets/pleural effusion still gone, liver mets had slight shrinkage. Largest hypodesne lesion is 2.1cm, 6 others 1cm or less.
Sept 13th-bone scan negative, mri revealed herniated disc.
Sept 27- Ct of brain, negative/lung mets still gone/ 2 liver lesions gone, 4 under 1cm, 1 @1.7cm.
Nov 29-CT shows stable, lungs still clear, liver tumors stable
Jan 11, 2005-CA27.29 23 / CEA 2.9
Jan 18th, Ct shows disease is still stable

New to stage 4: diagnosed November 20 with 1 spot 15 mm to lung and 3 nodes. Currently on Taxotere, Carboplatin, herceptin. Just had a CAT. Only the lung met is left and shrunk to 7MM. Onc is talking about swithing me after this cycle to Abraxine , Carboplatin and herceptin.
Mickey

Hi Lolly,

My wife Caryn was diagnosed with mets to lung and liver in July 04. Gemzar/Herceptin (Gemzar: 2 on 1 off and Herceptin continuous) has her clear and she has just stoppped the gemzar.

Hope your friend has as strong results with whatever treatment she tries.

Warmest regards,
Eric

I was dx with kung mets in 2003- very involved including paralized diaphragm and vocal cords -had 4 months of taxotere (every 3 weeks) and herceptin daily (am still on the herceptin) It worked very well and since then I have been NED in my lungs. Good luck and God Bless. Patty

My lung mets dx was almost 2 years ago - Feb 2003. The lung nodule I had was surgically removed. Treatment after that was Navalbine and Herceptin for about 6 months (Herceptin every week, Navalbine 3 weeks on 1 week off) then just Herceptin for another 9 months (1 treatment every 3 weeks - called a maintenance dose).

I have been NED since the surgery in 2003. I have not done any chemo - not even Herceptin - since July. Results of the PET scan I had 3 weeks ago were "all clear".

Peggy

My lung mets dx was almost 2 years ago - Feb 2003. The lung nodule I had was surgically removed. Treatment after that was Navalbine and Herceptin for about 6 months (Herceptin every week, Navalbine 3 weeks on 1 week off) then just Herceptin for another 9 months (1 treatment every 3 weeks - called a maintenance dose).

I have been NED since the surgery in 2003. I have not done any chemo - not even Herceptin - since July. Results of the PET scan I had 3 weeks ago were "all clear".

Peggy

[Lolly]

Thank you all for your responses, I am hoping this will be encouraging to my friend, to know there are others out there who have been in the same boat. I'll see her tomorrow. Thanks again!

Love, Lolly

Hi Lolly, I also have lung mets since Oct. 2002. I have tried many chemos but some only have worked for a very short while. I am presently on Xeloda/Herceptin. Maybe this is do it.