I think it is important to keep things in perspective.
Cancer of all sorts involves many pathways.
A great deal is not know.
Some agents like fats work at very fundmental levels.
Curcumin is reported to be an anti inflamatory (COX blocker). Like many food it may have multiple effects.
COX 2 pathways are reported to have a role in cancer. The COX pathways are very complex and what are are often commonly referred to as COX blockers may and do work on different areas within that frame work.
A number of studies are looking at low level cox blockers as part of a risk reduction treatement strategy.
BUT it is equally important to look at those things in our diet that were around a very long time before plant and date back to the veyr begining such as intake of fats and sugars (see posts on omega three sixes and sucrose) as well as the more commonly discussed topics.
From everthing I have read our departure from our dietary roots in very large margins in tems of fat intake amount and balance, refined sugars particularly fructose, along with other often cited factors are magors factors to be considered in terms of a risl reductio strategy.
This is an abstract from an exellent article which I recommend as a read.
Origins and evolution of the Western diet: health implications for the 21st century1,2
Loren Cordain, S Boyd Eaton, Anthony Sebastian, Neil Mann, Staffan Lindeberg, Bruce A Watkins, James H O’Keefe and Janette Brand-Miller
"In the United States and most Western countries, diet-related chronic diseases represent the single largest cause of morbidity and mortality. These diseases are epidemic in contemporary Westernized populations and typically afflict 50–65% of the adult population, yet they are rare or nonexistent in hunter-gatherers and other less Westernized people. Although both scientists and lay people alike may frequently identify a single dietary element as the cause of chronic disease (eg, saturated fat causes heart disease and salt causes high blood pressure), evidence gleaned over the past 3 decades now indicates that virtually all so-called diseases of civilization have multifactorial dietary elements that underlie their etiology, along with other environmental agents and genetic susceptibility. Coronary heart disease, for instance, does not arise simply from excessive saturated fat in the diet but rather from a complex interaction of multiple nutritional factors directly linked to the excessive consumption of novel Neolithic and Industrial era foods (dairy products, cereals, refined cereals, refined sugars, refined vegetable oils, fatty meats, salt, and combinations of these foods). These foods, in turn, adversely influence proximate nutritional factors, which universally underlie or exacerbate virtually all chronic diseases of civilization: 1) glycemic load, 2) fatty acid composition, 3) macronutrient composition, 4) micronutrient density, 5) acid-base balance, 6) sodium-potassium ratio, and 7) fiber content. However, the ultimate factor underlying diseases of civilization is the collision of our ancient genome with the new conditions of life in affluent nations, including the nutritional qualities of recently introduced foods."
http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
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