PTEN test

Sammy · 06-19-2006, 12:31 PM

I did read all the past articles. I still needed clarification , if the tumor is already removed then how do they test for PTEN ? Is there a Serum test for this like Her2 or is it only at tissue level ?

RobinP · 06-19-2006, 04:46 PM

Hi Sam,

I had my pTEN tested; it was positive- yahoo. I had my labatory that stores my tumor tissue block,forward some slices of the block to TMD- Targeted Molecular Diagnostics.Then TMD had the report back to me within days. Good luck.

Sammy · 06-20-2006, 10:04 AM

Thank you all for clarification. But, due to my ignorance I have another question. If the tumor is already excised then how does the PTEN test predict response of Herceptin. If herceptin still depends on PTEN after tumor excision then I guess it PTEN should be available by serum test also... ?

RobinP · 06-20-2006, 12:02 PM

If you have pTEN present or if you are pTEN positive that is a good thing as Herceptin activates pTEN so it can stop proliferation of the her2 postive cancer cell. As far as I know there is currently no serum pTEN test available; it is done on tissue block probably via Western blot assays.

06-22-2006, 09:34 AM

Thank you all for the valuable information.

IRENE FROM TAMPA · 06-24-2006, 09:14 AM

Robyn -

You stated that you sent your tissue sample to Target Molecular Diagnostics.

I would also like to have mine sample checked for PTen. Where is this place at and is that the only place to send to? How do you go about checking on this?
any help you can give me would be greatly appreciated.

Thanks

06-27-2006, 12:14 PM

www.tmdlab.com