Want everyone's opinion

[dskdrive]

Michelle,

The main thing for me is to live my life without any regrets or what if's. I feel that now is my chance to do whatever I can to keep this beast from reoccuring. I am Stage 2, Node neg, her2+, er+,pr+. I am now just over 6 months out of treatment. DX Sept. 04, Lump,chemo, rads. I am on Arimidex. I did not qualify for the vaccine trial. There was no Herceptin in my origional treatment plan. I pushed for it and began treatments every 3 weeks starting Sept. 05. I am satisified that I am doing all I can to win this fight for now.

[Christine MH-UK]

Hi Michelle,

I remember that way back in June somebody posted a piece in which Dr. Edith Perez (as I remember it) talked about the rationale behind giving herceptin for so long as a single agent and she said that it was because the evidence from mice had indicated that six months probably wouldn't do enough, but it wasn't clear how much was needed.

I wonder if they have moved towards cutting down on the herceptin tail because of the very high complete response rates that have been achieved in the trials of herceptin-based chemo.

At any rate, I hope that the HERA (non-US) trial two-year arm announces results early (like Her2 trials seem to do today). I had heard that the control arm of HERA was offered either one year of herceptin or randomisation to a one or two year arm, which would indicate that they might still think that two years has some effect, otherwise why not just give the control arm one year of herceptin as a consolation prize?

34 nodes positive is alot of nodes, so I would go for a second year.