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				Re: Revisiting pCR, partial response, and prognosis
			 
 Hi Lizbeth,
 Thanks for posting this.  I could really use your help!  I was diagnosed stage IIB, HER2+, ER-,PR- , one positive node, in Dec, 2014.  After receiving 6 rounds of TCHP and then a bilateral mastectomy 2 weeks ago, I just got my pathology report.  Unfortunately, I did not get a pCR (crushing!) though they said my response was pretty good -- the breast tumor was gone and cancer in my node was nearly gone- 4.5 mm left.  (8 other nodes removed- all clear). However, because of the cancer left on node, my doctor has suggested I go in for more chemo, AC this time, because she is worried about rogue cells in my body. I will do anything to reduce my risk of recurrence, but I'm super nervous that I didn't get pCR after what I've been reading in the research (and also about going on AC frankly).  Should I request they check the Ki-67?  Anything else I should be asking? What do you think about using AC at this point?
 Thank you!
 Amy
 San Francisco
 
				__________________47 yrs old
 DX 12/12/14
 HER2+, ER- PR- Stage IIb, Grade 3 tumor, discovered in axillary node
 12/30/14 started tx: Carboplatin, Taxotere, Herceptin and Perjeta
 5/14/15 Bilateral mastectomy
 Pathology: partial pCR- 4.5mm left in one node, breast tumor gone, other nodes clear.
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