effectiveness?

[Donna H]

Hi Becky-
I have my path report although I think it is written in a foreign language. Is this what you were asking - estrogen receptor positive, progestorone positve, HER2+. It is invasive ductal carcinoma, nottingham grade 3, glandular score 3, nuclear pleomorphism score 3 and mitotic rate score 2. No node involvement. I probably should have really read the report many months ago - unfortunately we sold our house and moved (8 hours away, different state), then my Dad died and my Mom moved in with us right after my surgeries. Then I started chemo etc. It's been a wild ride!

[Becky]

Yes. Alot of times it says how positive you are. For example, i am 50% estrogen poaitive but I am progesterone negative. Anyway, all "antihormonals" work best of you are positive for both which you are. I dont know the stats on survival improvement but it is significant as hormone positive cancer tends to recur later in the game. There is always an early peak but unlike hormone negative bc, there is a 5-8 year second peak. This peak is oddly about when the 5 years of tamoxifen/femara type drugs is over. Hence studies to take it 10 years. The 10 year tamoxifen study shows the 10 years is only marginally better at ten years but 10 years has a significant carryover effect. Giving added protection for many years thereafter. I highly recommend therapy. I have been on Arimidex for 9.5 years. I am figuring in september my doc will take me off. If you have side effects when on femara, you can switch to arimidex or aromoson or even tamoxifen. There is risk reduction but i cant tell you what it is

[Donna H]

I was 100% estrogen receptor positive, 1% progesterone positive and Her2 2+. On another page it lists the Pathologic Staging as pT2, N0 (sn), i- M-N/A