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Old 07-25-2010, 07:55 PM   #14
Cal-Gal
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Join Date: Jun 2009
Location: Los Angeles, CA
Posts: 309
Re: Herceptin and CA 27.29 tumor marker

Hi Weety,

So sorry you are going through this worry--

You can see since my initial worry in April that the following month the marker went down almost 6 points--it seems mine like yours tend to bounce around that same area.

I finished Herceptin about 6 weeks ago--and funny you should ask about this now--I was freaked out only about a week ago-after being off the Herceptin about 5 weeks, my marker jumped to 42.2--the Onc had me retest 2 days later and it was back within normal range--but still at 34---

I have read that the 38 normal set point is just that a set point and that some Onc's think it should be lower.

All I know is that if mine is within normal my Onc doesnt freak out--

As for ME--I am just making sure that I am diligent about reporting pains etc-and making sure I have all my scans on time!!

Don't know if we can do anything else?

Good luck--Hugs,

CA 27.29 Tumor Marker History Range 0.00-38.60
1/28/09 27.2—one week after surgery—two weeks prior to chemo
3/13/09 46.4
4/23/09 41.9
5/21/09 63.5—Chemo complete 5/28/09—Started Herceptin June 12, 2009
7/10/09 34.0
8/14/09 28.8
9/18/09 26.1
10/16/09 27.2
11/14/09 34.5
12/11/09 32.4
1/08/10 33.0
2/5/10 27.7
3/5/10 35.8
4/2/10 35.1
4/30/10 29.7
5/28/10 32.3 -completed Herceptin 6/4/10
7/14/10 42.2
7/16/10 34.4



__________________
DX: 11/08 Age: 53
Surgery: 1/09
Bilat Mastectomy, no reconstruction
ILC-4 tumors-1.7 cm,1.5 cm (2).8 cm
DCIS-11 cm
All tumors Grade 3
All tumors ER-0%/PR-0%
All tumors HER2+
IHC-all tumors Overexpression/borderline
FISH 2 tumors Her2-Negative
FISH 2 tumors Her2+ Equivocal
Stage I, 0/1 nodes
LVI-Indeterminate(treated as positive)
SPR Score 8/9
Ki-67 20%
BRCA genetic test 1/2=negative
Chemo: 6 rounds TAC Feb-June 2009 w/Neulasta
Herceptin: 6/12/09-6/4/10 52weeks
HNPCC genetic test: negative
Port Placement-9/23/09 Port Removal 6/25/10
Echo's every 3 months-All normal
2/09 Staging PET/CT showed 0.2 micronodule upper R lobe-lung-Onc does not think this is mets--
6/5/09 AND 10/09 CT scan 0.2 micronodule unchanged
1/10-PET/CT-uptake in nasopharynx-
1/10-MRI All normal
6/10-Bone Scan-clear
12/10-PET/CT-All Clear-NED
12/11-PET-All Clear-NED

12/12-PET-All Clear-NED
12/13-CT w/contrast Head, Torso-All Clear
12/14-CT w/contrast Head-All Clear
2/15-Core needle biopsy-R scar line

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