Invasive Lobular Cancer HER2+ve - anyone else?

Cal-Gal · 01-06-2010, 07:02 PM

I think the nuclear score is part of a 3 part series called an SBR Score

My path shows:

Tubule score+Nuclear score+Mitotic score=SBR Score

I had 4 ILC tumors:
All my Tubules are a 3--and all my Nuclears are a 3---3of4 Mitotics are a 2--and one is a 1.

Evidently the highest SBR Score is 9--I am 8/9 for 3 tumors and 7/9 in one tumor--

I am not sure what tubule-nuclear and mitotic are indicitive of---

SuePen · 01-06-2010, 07:21 PM

Mine was grade 3 made up of Nuclear grade 3, tubule formation 3 and Mitoses 3 which add up to 9 - ie grade 3. Just means it's very agressive. That's the highest grade they give.

I also had no lypmhovascular invasion which is apparently good.

It also said I had extensive lobular carinoma in situ surrounding the invasive tumour, so it sounds like it had just started turning bad.

Boy, am I lucky it was found so early, that's all I can say. I was told it was 11mm but it was actually elongated 11mm x 6mm x 7mm which as my husband says is equivalent to a 5mm circular shape.

Now I want an MRI of the other breast seeing lobular is so sneaky, but my onc said nothing would happen while I'm having treatment anyway. But I'll be asking for one later.