Herceptin/T-DM1 trial ?

Rich66 · 11-03-2009, 04:22 PM

Any thoughts on borderline levels of Her2 and T-DM1? My mom's primary years ago was technically Her2+ but her recurrence liver biopsy was borderline Her2 negative and strongly ER+. She has had Herceptin with Navelbine based on initially elevated serum her2 but that combo is failing her.

Carolyns · 11-03-2009, 04:36 PM

Hi Rich,

I am sorry to hear about your mom. As far as Her2 status. The sample of mine that the drug company insisted on using was very specific. In my case it was a sample that had been Her2++ which would have excluded me from the trial. When their labs retested it the sample was Her2+++ and I was accepted. I hope that I have me pluses right. Anyway, they cut the sample into many slices as I understand it and the Her2 status worked. Otherwise they would not have accepted me into this trial.

I have you and your Mom and family in my prayers.

Carolyn