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I am also wondering why drugs such as Herceptin can't be injected into the cerebral fluid and thus given access to the brain that way. I am no medical expert but was just wondering if any of you had any insight. "
There was a study several years ago in Germany of this procedure. I found the following article which describes that study:
Intrathecal Herceptin
Data was also released at this years San Antonio meeting from a phase II study of a drug being developed by Wyeth - Neratinib which is a small molecule drug similar to Tykerb and also crosses the BBB.
Regards
Joe