Lida, I did TCH and to be honest it's hard to know for sure which drug caused what? I know I blamed most of my side on the Taxotere. However I do think the Carboplatin was the main cause of the nasty taste I had in my mouth. It was just awful. Also I had almost a complete loss of appetite which I am pretty sure was the Carbo. Ended up with a sore mouth and had to take some meds for that. Also I felt really weak at times and I believe that was the Carbo too? (Maybe it was just the combo of both...again, its hard to say for sure?)
As to nausea I really had no problems at all with TCH. I know several other women said the same thing. I took my nausea meds to begin with to be on the safe side, but about the 3rd infusion I went off them and was just fine.
And yes the Carbo will cause you low platelets but they keep an eye on that with weekly labs. I did have terrible indigestion, & burning in my throat. But once I got a script for Protonix I had instant relief.  I also did have constipation but I took Senokot for that and that worked great. I think the TCH is a good choice for you and one that is doable as they say. Every body is different...we all can have different reactions as you know. But as far as the Carbo I think you will get through it ok.
I'm sure others will reply...quite a few have taken carbo on this board. Hang in there.
Chelee
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DX: 12-20-05 - Stage IIIA, Her2/Neu, 3+++,Er & Pr weakly positive, 5 of 16 pos nodes.
Rt. MRM on 1-3-06 -- No Rads due to compromised lungs.
Chemo started 2-7-06 -- TCH - - Finished 6-12-06
Finished yr of wkly herceptin 3-19-07
3-15-07 Lt side prophylactic simple mastectomy. -- Ooph 4-05-07
9-21-09 PET/CT "Recurrence" to Rt. axllia, Rt. femur, ilium. Possible Sacrum & liver? Now stage IV.
9-28-09 Loading dose of Herceptin & started Zometa
9-29-09 Power Port Placement
10-24-09 Mass 6.4 x 4.7 cm on Rt. femur head.
11-19-09 RT. Femur surgery - Rod placed
12-7-09 Navelbine added to Herceptin/Zometa.
3-23-10 Ten days of rads to RT femur. Completed.
4-05-10 Quit Navelbine--Herceptin/Zometa alone.
5-4-10 Appt. with Dr. Slamon to see what is next? Waiting on FISH results from femur biopsy.
Results to FISH was unsuccessful--this happens less then 2% of the time.
7-7-10 Recurrence to RT axilla again. Back to UCLA for options.
Last edited by Chelee; 12-03-2008 at 12:49 AM..
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