Bisphosphonates as preventative

[donocco5w4]

Forteo really isnt a long acting Biphosphonate. It is a synthetic parathyroid hormone deriviative. Biphosphanates work by decreasing Osteoclast activity. The osteoclasts are the bone cells that break down the skeletal structure. As far as I can tell Forteo works in a different manner. It seems to stimulate the Osteoblasts which are the cells that build up the skeletal matrix, rather than inhibiting the Osteoclasts that break it down.

Im not sure that Forteo has the same anti cancer action that the Biphosphanates seem to be demonstrating.

Paul (Pharmacist)

[Jackie07]

I am sure going to ask my oncologist my next appointment in early December. Since part of my cancer express estrogen, I am going to ask him about both bisphosphonates and whether it is time for me to switch from Tamoxifen to ? since I have been on it for 5 years.