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On some pathology reports the mitotic index is reported as it is part of a Nottingham score where histology, tubules and mitotic index scores (all ranging 1-3) are added to come to the Nottingham score (or Grade of cancer). A score of 1 for any of these is low, 2 is intermediate and 3 is high. So a mitotic score of 1 means that the cells are dividing slowly and a 3 is rapidly dividing.
I have heard that if you get a score of 2 in any area, you should make sure the slides are read at a big cancer center (ie: Sloan Kettering, Dana Farber, UCLA, MD Anderson etc) because it really takes expertise to read a 2 in any category (too much to be low, to little to be high) so you really have to have a "feel" for it.
I am a biochemist by education but worked as a chemist many, many years. Now, I still work in chemistry but in selling and marketing (currently raw materials for hydraulic fluids, brake fluids, transmission fluids and synthetic lubricants).
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Kind regards
Becky
Found lump via BSE
Diagnosed 8/04 at age 45
1.9cm tumor, ER+PR-, Her2 3+(rt side)
2 micromets to sentinel node
Stage 2A
left 3mm DCIS - low grade ER+PR+Her2 neg
lumpectomies 9/7/04
4DD AC followed by 4 DD taxol
Used Leukine instead of Neulasta
35 rads on right side only
4/05 started Tamoxifen
Started Herceptin 4 months after last Taxol due to
trial results and 2005 ASCO meeting & recommendations
Oophorectomy 8/05
Started Arimidex 9/05
Finished Herceptin (16 months) 9/06
Arimidex Only
Prolia every 6 months for osteopenia
NED 18 years!
Said Christopher Robin to Pooh: "You must remember this: You're braver than you believe and stronger than you seem and smarter than you think"
Last edited by Becky; 01-16-2008 at 08:28 PM..
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