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11-02-2007, 11:29 AM
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#1
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Senior Member
Join Date: Sep 2005
Location: Alaska
Posts: 2,018
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vaccinations and anti-inflammatories
I just had my flu and Pneumovax injections too and wondered whether I should or not. I worry about whether or not the inflammation response that occurs with vaccination is a problem of any significance. I don't understand well enough whether it is more important for a person who has had cancer to avoid the inflammation that comes with vaccines, or if the vaccine is more important. My thought was to take an anti-inflammatory (especially since my arm hurt from getting both shots in the same arm quite a lot). But then I wondered whether the inflammation response is necessary for some length of time for the vaccine to be fully effective?
Obviously what I don't know about this is greater than what I do know!
So.... I let the vaccine work its stuff until my arm felt so painful that I was awake at 2 AM unable to sleep before caving in and taking an 81-mg aspirin.... and then 2 hours later, another one.
Do any of those who are in the vaccine programs for HER2 know whether taking an anti-inflammatory is a better or worse thing to do when getting vaccinated for someone who has had cancer?
AlaskaAngel
P.S. Isn't it sad that something so universally important as the question that is being asked here about whether the immune system is permanently damaged by treatment is not clearly explained to us prior to treatment, after so many years of masses of humans going through the treatments?
Last edited by AlaskaAngel; 11-02-2007 at 11:31 AM..
Reason: added concern
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11-02-2007, 12:02 PM
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#2
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Senior Member
Join Date: Aug 2006
Posts: 3,380
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A.A. wrote:
"Isn't it sad that something so universally important as the question that is being asked here about whether the immune system is permanently damaged by treatment is not clearly explained to us prior to treatment, after so many years of masses of humans going through the treatments?"
You have clearly elucidated the single overriding reason I declined chemotherapy for Stage 1 bc, after learning that, as a post-menopausal, strongly hormonally positive patient, I would see the lowest percentage of benefit of any group from the tx.
Hopeful
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11-02-2007, 02:15 PM
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#3
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Senior Member
Join Date: Aug 2003
Location: Morris, IL
Posts: 3,507
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If indeed we are immune system compromised for a long period during and after chemo, or possibly forever, that would seem to be all the more reason to get the pneumovax and influenza vaccines, the pneumovax must be repeated every 5 years, the flu shot yearly...and this doesn't look promising for all the cases of MRSA that are showing up...and hospitals are full of it! Kind of scary seeing as how we all go there to get better....I carry a bottle of hand sanitizer with me wherever I go now....I just read that the one child who died from MRSA in the past week was immune compromised due to cancer.....
__________________
"Be kinder than necessary, for everyone you meet is fighting some kind of battle."
Hugs & Blessings
Sheila
Diagnosed at age 49.99999 2/21/2002 via Mammography (Calcifications)
Core Biopsy 2/22/02
L. Mastectomy 2/25/2002
Stage 1, 0.7cm IDC, Node Neg from 19 nodes Her2+++ ER PR Neg
6/2003 Reconstruction W/ Tissue Expander, Silicone Implant
9/2003 Stage IV with Mets to Supraclavicular nodes
9/2003 Began Herceptin every 3 weeks
3/2006 Xeloda 2500mg/Herceptin for recurrence to neck nodes
3/2007 Added back the Xeloda with Herceptin for continued mets to nodes
5/2007 Taken Off Xeloda, no longer working
6/14/07 Taxol/Herceptin/Avastin
3/26 - 5/28/08 Taxol Holiday Whopeeeeeeeee
5/29 2008 Back on Taxol w Herceptin q 2 weeks
4/2009 Progression on Taxol & Paralyzed L Vocal Cord from Nodes Pressing on Nerve
5/2009 Begin Rx with Navelbine/Herceptin
11/09 Progression on Navelbine
Fought for and started Tykerb/Herceptin...nodes are melting!!!!!
2/2010 Back to Avastin/Herceptin
5/2010 Switched to Metronomic Chemo with Herceptin...Cytoxan and Methotrexate
Pericardial Window Surgery to Drain Pericardial Effusion
7/2010 Back to walking a mile a day...YEAH!!!!
9/2010 Nodes are back with a vengence in neck
Qualified for TDM-1 EAP
10/6/10 Begin my miracle drug, TDM-1
Mixed response, shrinking internal nodes, progression skin mets after 3 treatments
12/6/10 Started Halaven (Eribulen) /Herceptin excellent results in 2 treatments
2/2011 I CELEBRATE my 9 YEAR MARK!!!!!!!!!!!!!
7/5/11 begin Gemzar /Herceptin for node progression
2/8/2012 Gemzar stopped, Continue Herceptin
2/20/2012 Begin Tomo Radiation to Neck Nodes
2/21/2012 I CELEBRATE 10 YEARS
5/12/2012 BeganTaxotere/ Herceptin is my next miracle for new node progression
6/28/12 Stopped Taxotere due to pregression, Started Perjeta/Herceptin
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11-02-2007, 02:23 PM
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#4
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Senior Member
Join Date: Oct 2005
Location: LAND OF YES!
w/home in Boca Raton, Florida
Orig from L.I., N.Y.
Ever hovering IN THE NOW...
Posts: 1,904
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I Think We Must Always Protect Ourselves...
This question of suppressed immune system potentially forever is why I take the immune boosting supplements I do. And I get the flu vaccine ea yr. I didn't have residual pain in my arm after this shot and though glad, wonder... Why??? I think we must protect ourselves as best as possible.
I prefer HUGS to handshakes. Really! Hugs are very therapeutic. Whereas handshakes... I flush toilets w/the bottom of my shoe. I push doors open w/elbow if possible. I try not to get crazy.  I smile a lot. And laugh every day!
Andi
__________________
Andi BB
'95 post-meno dx Invasive LOBULAR w/9cm tumor! YIKES + 2/21 nodes. Clear mammo 10 mnths earlier. Mastec/tram flap reconst/PORT/8 mnths chemo (4Adria/8CMF). Borderline ER/PR. Tamoxifen 2 yrs. Felt BLESSED. I could walk and talk, feed and bathe myself! I KNEW I would survive...
'98 -- multiple mets to liver. HER2+ 80%. ER/PR- Raging, highly aggressive tumors spreading fast. New PORT. 9 mnths Taxotere Fought fire w/fire! Pronounced in cautious remission 5/99. Taxotere weekly for 6 wks, 2 wks off -- for 9 mnths. TALK ABOUT GRUELING! (I believe they've altered that protocol since those days -- sure hope so!!)
+ good old Vit H wkly for 1st 3 yrs, then triple dosage ev 3 wks for 7 yrs more... The "easy" chemo, right?! Not a walk in the park, but not a freight train coming at 'ya either...
Added Herceptin Nov '98 (6 wks after FDA fast-tracked it for met bc). Stayed w/Vit H till July '08! Now I AM FREE! Humbly and eternally grateful for this life-saving drug! NED since '99 and planning on keeping it that way. To hell w/poor prognosis and nasty stats! STOPPED VIT H JULY '08...! REMAIN STABLE... Eternally grateful...Yes is a world & in this world of yes live (skillfully curled) all worlds ... (e e cummings) EVERY DAY I BEAT MY PREVIOUS RECORD FOR # OF CONSECUTIVE DAYS I'VE STAYED ALIVE. Smile KNOWING you too can be a miracle. Up to me and God now...
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11-02-2007, 03:43 PM
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#5
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Senior Member
Join Date: Sep 2005
Location: Newton, MA
Posts: 951
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Exposure
I teach third grade and come in contact with of lot of colds, strep, etc. Since I am stage 4, I am always in treatment. I feel that my immune system is strengthened by the exposure I receive. It is similar to what happens to new parents with children who attend day care or preschool. The first year everyone is sick in the family, but eventually the parent's immune system is stronger. This also happens with first year teachers. They are often sick in during their first year of teaching.
I know we have to be careful, but I don't think it hurts to get out and live the lives we desire.
Best regards,
Barbara H.
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