Taxol and Her2 +
Dear members: I have read the article itself in New England Journal of Medicine and as Becky already indicated, Taxol very significantly benefitted HER2+ patients regardless of hormone status. (Recurrance reduced by 41% for Her2+ patients.) Patients were recruited between 1991 and 1995, and hence herceptin was not available to any of these patients.
So exactly how much taxol benefits in the presence of herceptin is unknown but intuitively one would expect it to be very significant. (This is at least what I hope since my wife received 16 weeks of neoadjuvant taxol herceptin with complete clinical but not pathological response).
The same study also showed that higher dose of doxorubicin (adrymycin) than standard did not have any additional benefit.
I want to indicate that I have been following this group for the last eight months and we benefitted enormously. I am emazed how much useful info is available here. We adjusted our lifestyle, diet habits etc. based on what I learned from this website. And I feel we were able to ask much better questions to my wife's oncologists because of what we learned from you. Just wanted to let you know that a lot more people benefit from the discussions here than you might realize.
Best regards....
Tayfun
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