Taxol does not for most bc, today's headline

Jean · 10-11-2007, 05:10 AM

Lani, once again thank you for your research and detailed information.
Just this morning on NBC (East coast time 7:15) there was a NYU onc.
on air, speaking about the different types of bc and the chemo trt that
would be best to choose for a patients type of cancer. We are now
beginning to hear more of this ...the shoe does not fit all feet.
I am happy to hear this information being supplied to the public.
Just a short time ago (4/05 when I was dx) discussions on different
subtypes were not what the onc. were discussing with their patients.
I had to reach out to this wonderful site to truly learn the details
of HER2...

We as HER2 bc patients must keep ourselves updated and informed
and not believe the "the sky is falling upon our heads".

Enjoy the Day!
God Bless
Jean

Becky · 10-11-2007, 06:17 AM

I saw the original study given by the researcher at ASCO 2006. Both the original presentation and the published results (read all the articles published on the board right now including the one on Articles of Interest posted by Mgarr (Mary)). Taxol gives benefit for all Her2+ patients REGARDLESS of hormone status. In the actual presentation of results, the difference in benefit between Her2+ patients that are hormone negative versus hormone positive was not significant, therefore the results of benefit are the same.

Because of seeing this paper firsthand, when Stage 1 women ask whether they should include taxol (as in the past many stage 1 women only receive 4 AC treatments followed by Herceptin), I have posted this original study stating, if given a choice, take the taxol too - it is the KEY ingredient.

Secondly - I believe this is why the TCH treatment works just as well as the AC followed by TH. It is the Taxol that is the more important chemo! More true research needs to be done to confirm this or more time needs to pass on current studies and long term results but I believe they will find that taxanes are key for Her2+ disease (regardless of hormone status) and for triple negative disease.