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Dear tdonnelly,
I suspect your bone pain is coming from the Neupogen you're likely getting while on Taxol to stimulate your white blood cells, which are destroyed by the Taxol. These cells are made within your bone marrow, and the pain comes from the stimulation of these cells. You shouldn't have this when on your Herceptin alone. I'd also like to suggest that your rectal bleeding may result from the severe constipation that Taxol can cause. Try taking stool softeners every day and drinks lots of water. I had your side effects while on Taxol and Herceptin, but on herceptin alone I've only had stiffness in my hands and feet after waking in the morning. Good luck and hang in there!
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