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07-21-2007, 10:25 PM
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#1
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Senior Member
Join Date: Oct 2005
Location: southern california
Posts: 287
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Hi,
I am just wondering how the mets to the lungs was confirmed? I have had CT's that showed multiple nodules to both peripheral lung lobes and I have had multiple Dr's say that the nodules could be scar tissue. I just was curoious as to the final evaluation. Did you have a biopsy? I am forever hopeful that your treatment goes as planned. You seem to be a very enspiring person on this site and I have read many of your posts and responces. I wish you well in this and will look for updates on your progress.
Alice
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07-22-2007, 12:19 AM
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#2
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Senior Member
Join Date: Nov 2004
Location: Streetsboro, Ohio
Posts: 365
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I was on TCH 3 years ago and had a very positive result. My CA15 tumor markers, which were 345 at diagnosis were normal after 4 months of tx.. I also had the same weekly schedule which was easier on my body. I didn't lose all my hair and it started to grow back the 5th month of treatment. I also didn't have as much aches and pains. I'll continue to pray that you will have healing. Love and Blessings, Lu Ann.
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07-22-2007, 08:09 AM
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#3
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Senior Member
Join Date: Feb 2006
Location: Acworth, GA
Posts: 2,104
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Thank you everyone for your words of encouragement.
Alice, it was determined to be lung mets via the amount of uptake in the nodes. No biopsy is scheduled at this time - thank God, as I understand that's not too comfortable a thing.
The "big guns" as my oncologist put it refers to the Tykerb, Xeloda combo. Hopefully I won't need them.
I'm just hoping that Taxol will be esier on me than the Taxatore!
But, whatever the side effects I'm ready for the fight!
__________________
Kate
Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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07-22-2007, 11:21 AM
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#4
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Senior Member
Join Date: Oct 2005
Posts: 3,519
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Kate- Taxol was MUCH easier for me than Taxotere. (though I had Taxotere with Big Red and Cytoxan, so it's hard to determine which was the most evil of all...)
My only noticeable side effects on Taxol were fatigue and the periperal neuropathy of numb fingertips and numb toes and balls of my feet. That has already pretty much cleared up for me after only 4 months off of Taxol. And glutamine is very helpful for mitigating the numbness, and no interference with the chemo. (one scoop glut. powder in a shot of juice 3xday). B6/BComplex are also very helpful, but I believe you can't take it 24 hours prior to Carbo or 5 days post Carbo due to interference.
The Carbo gave me the mildest form of queasiness for about 2 days after a treatment, but totally tolerable. Oh and the ever popular baldie renaldie look. (and with Carbo in the mix, my hair didn't grow at all like the sprigs that came in on Taxol alone)
The Herceptin caused the hallmark drippy nose and drippy eyes. (Patanol eyedrops seemed to help)
__________________
Brenda
NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)
Nov'03~ dX stage 2B
Dec'03~ Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~ Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~ micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~ micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg
Apr'07~ MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~ Started Tykerb/Xeloda, no WBR for now
June'07~ MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~ MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~ PET/CT & MRI show NED
Apr'08~ scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~ MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~ dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~ Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~ new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~ new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~ 25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.
"I would rather be anecdotally alive than statistically dead."
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07-22-2007, 08:40 PM
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#5
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Senior Member
Join Date: Dec 2006
Location: Oregon
Posts: 715
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Kicking Butt and Kicking Mules
Kate,
I have this image of all of us standing in a line and kicking like mules. Really makes me smile.
I am glad that "our team." agrees with your doctor's recommendation for the TCH. I am also glad to hear that some say TCH is easier to tolerate than A/C.
I agree, a margarita would taste better than all the cocktails they give us.
You go girl, Hugs, Catherine
__________________
Catherine
Found my own lump in the shower
April 2006 at the age of 58
Stage IIB, ER- PR- HER2+++ multi focal tumors, largest 2.3cm
Chemo first: AC/Taxol over 16 weeks
Bilateral mastectomy Sep 06
33 rads after the surgery
1 year of Herceptin completed Dec 07
15 years and no recurrence as of April 2021
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07-23-2007, 12:53 AM
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#6
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Senior Member
Join Date: Oct 2005
Posts: 3,519
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If we could invent Vanilla Latte flavored barium and convince the nurses to drip Margaritas along with our chemo, we might be on to something!
__________________
Brenda
NOV 2012 - 9 yr anniversary
JULY 2012 - 7 yr anniversary stage IV (of 50...)
Nov'03~ dX stage 2B
Dec'03~ Rt side mastectomy, Her2+, ER/PR+, 10 nodes out, one node positive
Jan'04~ Taxotere/Adria/Cytoxan x 6, NED, no Rads, Tamox. 1 year, Arimadex 3 mo., NED 14 mo.
Sept'05~ micro mets lungs/chest nodes/underarm node, Switched to Aromasin, T/C/H x 7, NED 6 months - Herceptin only
Aug'06~ micro mets chest nodes, & bone spot @ C3 neck, Added Taxol to Herceptin
Feb'07~ Genetic testing, BRCA 1&2 neg
Apr'07~ MRI - two 9mm brain mets & 5 punctates, new left chest met, & small increase of bone spot C3 neck, Stopped Aromasin
May'07~ Started Tykerb/Xeloda, no WBR for now
June'07~ MRI - stable brain mets, no new mets, 9mm spots less enhanced, CA15.3 down 45.5 to 9.3 in 10 wks, Ty/Xel working magic!
Aug'07~ MRI - brain mets shrunk half, NO NEW BRAIN METS!!, TMs stable @ 9.2
Oct'07~ PET/CT & MRI show NED
Apr'08~ scans still show NED in the head, small bone spot on right iliac crest (rear pelvic bone)
Sept'08~ MRI shows activity in brain mets, completed 5 fractions/5 consecutive days of IMRT to zap the pesky buggers
Oct'08~ dropped Xeloda, switched to tri-weekly Herceptin in combo with Tykerb, extend to tri-monthly Zometa infusion
Dec'08~ Brain MRI- 4 spots reduced to punctate size, large spot shrunk by 3mm, CT of torso clear/pelvis spot stable
June'09~ new 3-4mm left cerrebellar spot zapped with IMRT targeted rads
Sept'09~ new 6mm & 1 cm spots in pituitary/optic chiasm area. Rx= 25 days of 3D conformal fractionated targeted IMRT to the tumors.
Oct'09~ 25 days of low dose 3D conformal fractionated targeted IMRT to the bone mets spot on rt. iliac crest that have been watching for 2 years. Added daily Aromasin back into treatment regimen.
Apr'10~ Brain MRI clear! But, see new small spot on adrenal gland. Change from Aromasin back to Tamoxifen.
June'10~ Tumor markers (CA15.3) dropped from 37 to 23 after one month on Tamoxifen. Continue to monitor adrenal gland spot. Remain on Tykerb/Herceptin/Tamoxifen.
Nov'10~ Radiate positive mediastinal node that was pressing on recurrent laryngeal nerve, causing paralyzed larynx and a funny voice.
Jan'11~ MRI shows possible activity or perhaps just scar tissue/necrotic increase on 3 previously treated brain spots and a pituitary spot. 5 days of IMRT on 4 spots.
Feb'11~ Enrolled in T-DM1 EAP in Denver, first treatment March 25, 2011.
Mar'11~ Finally started T-DM1 EAP in Denver at Rocky Mountain Cancer Center/Rose on Mar. 25... hallelujah.
"I would rather be anecdotally alive than statistically dead."
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07-23-2007, 06:07 AM
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#7
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Senior Member
Join Date: Jan 2007
Posts: 144
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Kate,
Now you have a plan of attack and I know that is just what you will do. Thanks for keeping us in the loop. I was thinking about all day. I hope this treatment is easy on you and that you remain as optimistic as you sound.
Postive thoughts coming your way,
Emelie
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