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I had really bad cramps in the beginning - I'm over the 2 year mark - and they are still happening, but not as bad. I'm not sure if it is because my body has gotten used to the Herceptin - or if I don't stretch my legs in my sleep like I used to (that always set off a cramp). I used to love to point my toes and get a good stretch in when I woke up in the morning - and that just spells disaster for me (leg and foot crams) now.
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