Yeah Tykerb started

H&B · 06-30-2007, 10:45 PM

Hi all

Just quickly thank you for your responses, My wifes headaches have started to subside and she is seeing some definate reductions in her tumors that she can feel with her fingers. She is delighted and is managing well with the diahrea, hot feet and hands, her main thing is she is so fatigued she is spending most of her day in bed & sleeping,
She has hope and that is the main thing!!we are so thankful its hard to put into words.
May you all continue to have wonderful results on a targeted therapy - the way of the future!!

hutchibk · 06-30-2007, 11:08 PM

HI Harald - she should not be taking any supplements with folic acid. It can be found in multivitamins and B-complex... it can make the side effects worse, so don't take it! Also, no grapefruit! I find that eating as clean and healthy as possible really mitigates the diarrhea severity. Also, try a B.R.A.T. breakfast everyday... banana, rice, applesauce, toast and tea. It works for me. I only have about 1-2 bad diarrhea days every month so far, and usually when I get lazy dietarily. Also, as mentioned by others here, dosage can be adjusted to mitigate side effects. Hydration can be a cause of headaches and leg cramps.

The hot feet and palms of hands is Hand/Foot syndrome. Take 100 mg of B6 (50m in the AM and 50m in the PM). Don't let it get out of hand. Have her do what she can now to prevent it! Once it takes hold, it's hard to go back.

Best of luck to you and Brony! Australia? I might be there in November!

doh2pa · 07-01-2007, 06:51 AM

Hi Harald,

Love your picture, by the way.

I wanted to address a question in your original post about reversal of lung mets on this regimen. I am on Tykerb and Xeloda and after only 6 weeks, my scans on Friday showed 3 small lung mets are GONE!!! I greatly hope that your wife will have the same amazing results, sounds like she is well on her way.

Donna