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I am involved in a NCCTG Phase III study to determine whether Urea/Lactic Acid Based Cream and Vitamin B-6 are effective for prevention of Xeloda induced hand and foot syndrome. It is a double blind study so I don't know if I have the real thing or placeabos. I have to rub 1/2 tsp of the lotion on the bottoms of my hands and feet twice a day, let it set 5 minutes before I do anything and take the B-6 (if it is) tablet once a day. I have to keep a daily diary of the symptoms. I just started with this yesterday so I can't give you any thoughts on how my hands/feet are doing.
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Andi
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Stage IIIC, 17 of 20 Nodes +, E+, Her2+++
Diagnosed 6/30/05
Lumpectomy 7/13/05
Dose Dense A/C x 4
Weekly Taxol + Herceptin x 12
Remainder of year Herceptin Every 3 weeks (completes 9/13/06)
Radiation completed 2/28/06
Currently on Tamoxifen
Dec 06 - Pleural effusion treated with pleurodesis
Now er/pr-, her2++
1/07 started weekly Navelbine plus Herceptin
Discontinued Tamoxifen
4/27/07 CTshowed progression
5/01/07 Began Tykerb/Xeloda + Zometa
5/22/07 Stopped treatment due to great progression
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