FISH numbers? I"m at Project LEAD

astrid · 03-04-2007, 10:27 AM

IHC 2+ ; FISH 3.4; getting Herceptin every three weeks for a year June 06 to June 07

Marlys · 03-04-2007, 10:42 AM

I am Her2+++. Fish was not done.
Marlys

Bev · 03-04-2007, 09:56 PM

IHC 3+, Fish+. Being FISH+ was no surprise to anyone. Doc doesn't believe in worrying us with the minutiae of the actual score On one hand I think I would like all the info, but on the other I would have flipped if I closely tracked my MUGA dropping.

Grace, I think oncotype is geared to early stage, node negative. Almost all HER2+ yield high onco score with ER/PR- not helping.

Looking forward to the day thet have all the answers. Bev

Linda · 03-04-2007, 10:46 PM

I was only tested by FISH and -- 9.6. Also very high ki67, myotic rate, the whole ball of wax. My path report was a column of "unfavorables." The tumor grew VERY fast.
Almost at two years and NED.
Linda.

Melinda · 03-06-2007, 09:00 PM

Grace
I just came across an interesting article that may explain the differences in FISH testing by different labs. http://www.nccn.org/patients/fact_sheet.asp. I will however ask my ONC what my ratio is. I found it curious that he just said 'positive"
Melinda

03-06-2007, 09:28 PM

Thanks Melinda. Jill's husband posted the same site today on another thread and I found it excellent, the best explanation I've read to date of HER2 and the various ways of testing for over-expression and amplification.