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My understanding is the more FISH+/IHC3+ you are, the more likelihood there is of herceptin being effective.
In my own case with a weakly positive FISH score (2.71) and an IHC score of 2+, there was no question of me having herceptin, given that I did not receive chemo either.
I am a year out, and so far, so good...
Mcgle (UK)
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