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Old 08-31-2006, 07:19 PM   #1
mindersue
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How about Aromasin and low blood counts, or radiation and low blood counts?

Grasping for straws,

Mindy
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Old 08-31-2006, 07:52 PM   #2
tousled1
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I'm not on Aromasin so I can't say how it affects blood counts. When I was on A/C and then Taxatore my red and white counts were always low. Then I was getting shots of Neulasta the day after chemo and Procrit the day of chemo.
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Stage IIIC Diagnosed Oct 25, 2005 (age 58)
ER/PR-, HER2+++, grade 3, Ploidy/DNA index: Aneuploid/1.61, S-phase: 24.2%
Neoadjunct chemo: 4 A/C; 4 Taxatore
Bilateral mastectomy June 8, 2006
14 of 26 nodes positive
Herceptin June 22, 2006 - April 20, 2007
Radiation (X35) July 24-September 11, 2006
BRCA1/BRCA2 negative
Stage IV lung mets July 13, 2007 - TCH
Single brain met - August 6, 2007 -CyberKnife
Oct 2007 - clear brain MRI and lung mets shrinking.
March 2008 lung met progression, brain still clear - begin Tykerb/Xeloda/Ixempra
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Old 08-31-2006, 08:34 PM   #3
chrisy
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Mindy,
It can take some time for your blood counts to rebound after chemo. Are they continuing to drop on Aromasin/Herceptin or just not getting better? I've no experience with Aromasin, but have been on Herceptin alone for a year and a half and my blood counts have stayed pretty good.
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June 2002 extensive hi grade DCIS (pre-cancer-stage 0, clean sentinal node) Mastectomy/implant - no chemo, rads. "cured?"
9/2004 Diag: Stage IV extensive liver mets (!) ER/PR- Her2+++
10/04-3/05 Weekly Taxol/Carboplatin/Herceptin , complete response!
04/05 - 4/07 Herception every 3 wks, Continue NED
04/07 - recurrence to liver - 2 spots, starting tykerb/avastin trial
06/07 8/07 10/07 Scans show stable, continue on Tykerb/Avastin
01/08 Progression in liver
02/08 Begin (TDM1) trial
08/08 NED! It's Working! Continue on TDM1
02/09 Continue NED
02/10 Continue NED. 5/10 9/10 Scans NED 10/10 Scans NED
12/10 Scans not clear....4/11 Scans suggest progression 6/11 progression confirmed in liver
07/11 - 11/11 Herceptin/Xeloda -not working:(
12/11 Begin MM302 Phase I trial - bust:(
03/12 3rd times the charm? AKT trial

5/12 Scan shows reduction! 7/12 More reduction!!!!
8/12 Whoops...progression...trying for Perjeta/Herceptin (plus some more nasty chemo!)
9/12 Start Perjeta/Herceptin, chemo on hold due to infection/wound in leg, added on cycle 2 &3
11/12 Poops! progression in liver, Stop Perjeta/Taxo/Herc
11/12 Navelbine/Herce[ptin - try for a 3 cycles, no go.
2/13 Gemzar/Carbo/Herceptin - no go.
3/13 TACE procedure
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Old 08-31-2006, 09:15 PM   #4
mindersue
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Thanks for the responses. My counts were low in July and lower today, after being on Aromasin for 2 weeks. My pharmacist friend said that Aromasin can cause counts to drop (about 20% of the time), as well as radiation.

I have to admit it freaked me out a little bit. : ) It just seems like they're going the wrong way. I'll wait and see how they come back in a week.

Thanks again, you guys are great!
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