my new Unicorn
Dear Ladies,
The biopsy an blood results are back and this coming Monday(17th) Iwill receive my first dose of the shinogi and if I react well to this Japonese drug on phase 1b then this is to become my new Unicorn. I say unicorn as oppose to Trojan horse because it carries a lot of my dreams..
The results are good I think for a phase 1a. A small half of patients are showing some sort of responses (at escalating dose) with one complete response from a Her2 BC patient (out of 19 patients trialled) with 2pts on it over> 12 months. I am now on the phase 1b (i.e we know the dose)
http://www.asco.org/ASCOv2/Meetings/...stractID=93825
I am always so tired now and in turn I find it quite isolating, lucky I have the sweetest and funniest dog in the world with me. So I pray that this give me a break, a long break, a long long break... Please send me good words and wishes and healing thoughts that this will work for me because sometimes it's hard to keep my hopes up and I always used to have limited faith in inhibitors.. I want to be proven so very wrong.
__________________
35 y/o
June 06: BC stage I
Grade 3; ER/PR neg
Her-2+++; lumpectomies
Aug 06: Stage IV
liver mets: 6 tumours
July 06 to Jan 07: 2*FEC+6*Taxotere; 3*TACE; LITT
March 07- Sept 07: Vaccination trial (phase 2, peptide based) at the UW (Seattle).
Herceptin since 2006
NED til Oct 09
Recurrence Oct 2009: to internal mammary gland since October 2009 missed on Oct and March 2010 scan.. palpable nodes in May 2010 when I realised..
Nov 2011:7 mets to lungs progressing fast failed hercp/tykerb/xeloda combo..
superior vena cava blocked: stent but face remains puffy
April 2012: Teresa Trial, randomised to TDM1
Nov 2012 progressing on TDM1
Dec 2012 blockage of my airways by tumours, obliteration of these blocking tumours breathing better but hoping for more- at mo too many tumours to count in the lungs and nodes.
Dec 2012 Starting new trial S-222611 phase 1b dual egfr her2+ inhibitor.
'Under no circumstances should you lose hope..' Dalai Lama
Last edited by fullofbeans; 12-13-2012 at 06:33 PM..
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