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Old 02-24-2010, 12:18 PM   #1
Emelie B
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Join Date: Jan 2010
Posts: 170
T-DM1 Trials

I was able to contact the patient coordinator for a trial that is going on in my back door, and I am on the list for a potential spot.
Since I have not yet had Tykerb/Xeloda, I really don't qualify for this trial, but should I progress on the combo, I will be easily qualified.
She also mentioned to me a trial for the drug Array. Said it is new and in beginnig trials. Specifically for Her2 ladies also.
I am continuing with the Hercpetin and Taxol with once a month Zolada.
Do have one major problem this time. My face has a bright red rash across the forhead and down my nose to both sides of my cheeks. Nurse said it was from the Decadron. She also said they will reduce the amount since I am so sensitive. Who knew?
Anyone else experience this?
Take care all,
Emelie
__________________
Nov. 2006-IDC with Her2 +++
A/C for 3 rounds
Dec. 2006- Herceptin and Taxotere
March 2007-MRM with 8 of 14 lymph node involvement
May 2007-36 Rads
Sept. 2007- Stopped Herceptin
Jan. 2010- CT scan shows enlarged lymph nodes in sternum and lung involvement
Feb. 2010-PET scan shows mets to liver, lung, lymph nodes and bone
Feb. 2010- Started Herceptin/Taxol and Zometa
April 2010-PET scan clear. Herceptin and Zometa
June 2010- Stopped Herceptin continue Zometa and still NED
August 2010-Back on Herceptin and Zometa every 3 weeks
August 13, 2010- Had another port placed
August 24, 2010- PET scan clear. Herceptin and Zometa every three weeks
Nov. 2010-PET scan clear
Feb. 2011-Brain MRI clear
March 2011- PET scan clear
May 2011- PET scan clear
Sept. 2011- PET, Mammo, Bone Scan all clear- Herceptin only
March 2012-Recurrence in lungs and tumor around pota hepatis artery. Added Navelbine to herceptin
April 2012- Entered palliative care
June 5, 2012-Entered hospice care
Planning my memorial
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Old 02-24-2010, 02:21 PM   #2
Ellie F
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Join Date: Feb 2009
Posts: 1,526
Re: T-DM1 Trials

Hi Emelie
Glad you have got some good news about t-dm1 trials.

I had a bright red rash just as you have described whilst on taxotere and herceptin. It was Chelee in fact that responded and said the same thing had happened to her.
My onc also wondered if it was the steroids but I am convinced it was the taxane.I tried numerous things including cold compresses and a mild steroid cream but they didn't work. Eventually I realised that the sun was a trigger so I avoided it as much as possible and wore a very high factor sun cream and secondly bought a anti histamine cream from the pharmacy which really calmed it down.
Mine was so noticable that people thought i'd been burned and I thought it would never go! Once I stopped taxotere it gradually faded away.
One interesting thing was I didn't take the steroid before my last dose but still got the rash, that's what convinces me it was taxotere rather than the steroid.

Hope this is some help.
Ellie
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