HER2 Support Group Forums - View Single Post - From HER+ back to ER+: how to diagnostic?

al from Canada · 05-02-2006, 04:13 PM

One thing we do know is that HER2 and ER status is variable and may change as the disease progresses. This has major implications for HER2 (-) BC as many may have HER2++ as the disease changes and do not know it and may have benefit grom herceptin. ER+ resistance can be reversed with administration of a HER1 inhibitor such as iressa, lapatinib or tarceva.

Al

05-02-2006, 04:13 PM	#3
al from Canada Senior Member Join Date: Jul 2005 Location: Ontario, Canada Posts: 722	One thing we do know is that HER2 and ER status is variable and may change as the disease progresses. This has major implications for HER2 (-) BC as many may have HER2++ as the disease changes and do not know it and may have benefit grom herceptin. ER+ resistance can be reversed with administration of a HER1 inhibitor such as iressa, lapatinib or tarceva. Al __________________ Primary care-giver to and advocate for Linda, who passed away April 27, 2006.