Forteo really isnt a long acting Biphosphonate. It is a synthetic parathyroid hormone deriviative. Biphosphanates work by decreasing Osteoclast activity. The osteoclasts are the bone cells that break down the skeletal structure. As far as I can tell Forteo works in a different manner. It seems to stimulate the Osteoblasts which are the cells that build up the skeletal matrix, rather than inhibiting the Osteoclasts that break it down.
Im not sure that Forteo has the same anti cancer action that the Biphosphanates seem to be demonstrating.
Paul (Pharmacist)
|