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Senior Member
Join Date: Mar 2006
Posts: 4,783
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pubmed check of monoclonal antibodies, hypomagnesemia
--it has been described for EGFR(her1) monoclonal antibodies mainly (cetuximab), but it is unclear whether tykerb which blocks her1 and her2
may have a similar effect , let alone herceptin
Disorders of renal magnesium handling explain renal magnesium transport.
J Nephrol. 2007 Sep-Oct;20(5):507-10. Review.
PMID: 17918133 [PubMed - indexed for MEDLINE]
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Related Articles, LinksJin JP, Chong SM, Hossain MM.
Related Articles, LinksGroenestege WM, Thébault S, van der Wijst J, van den Berg D, Janssen R, Tejpar S, van den Heuvel LP, van Cutsem E, Hoenderop JG, Knoers NV, Bindels RJ.
Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia.
J Clin Invest. 2007 Aug;117(8):2260-7.
PMID: 17671655 [PubMed - indexed for MEDLINE]
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Related Articles, LinksMuallem S, Moe OW.
When EGF is offside, magnesium is wasted.
J Clin Invest. 2007 Aug;117(8):2086-9.
PMID: 17671646 [PubMed - indexed for MEDLINE]
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Related Articles, LinksTejpar S, Piessevaux H, Claes K, Piront P, Hoenderop JG, Verslype C, Van Cutsem E.
Magnesium wasting associated with epidermal-growth-factor receptor-targeting antibodies in colorectal cancer: a prospective study.
Lancet Oncol. 2007 May;8(5):387-94.
PMID: 17466895 [PubMed - indexed for MEDLINE]
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Related Articles, LinksFakih M.
Anti-EGFR monoclonal antibody-induced hypomagnesaemia.
Lancet Oncol. 2007 May;8(5):366-7. No abstract available.
PMID: 17466890 [PubMed - indexed for MEDLINE]
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Related Articles, LinksPerrin C, Fabre C, Raoul JL, Boucher E.
Behavioral disorders secondary to profound hypomagnesemia in a patient given cetuximab for metastatic colorectal cancer hypomagnesemia due to cetuximab treatment.
Acta Oncol. 2006;45(8):1135-6. No abstract available.
PMID: 17118852 [PubMed - indexed for MEDLINE]
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Related Articles, LinksFakih MG, Wilding G, Lombardo J.
Cetuximab-induced hypomagnesemia in patients with colorectal cancer.
Clin Colorectal Cancer. 2006 Jul;6(2):152-6.
PMID: 16945172 [PubMed - indexed for MEDLINE]
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Related Articles, LinksAltundag K, Altundag O, Baptista MZ, Turen S, Atik MA.
Re: Cetuximab therapy and symptomatic hypomagnesemia.
J Natl Cancer Inst. 2005 Dec 7;97(23):1791-2. No abstract available.
PMID: 16333039 [PubMed - indexed for MEDLINE]
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Related Articles, LinksSilverstein DM, Aviles DH, LeBlanc PM, Jung FF, Vehaskari VM.
Related Articles, LinksSchrag D, Chung KY, Flombaum C, Saltz L.
Cetuximab therapy and symptomatic hypomagnesemia.
J Natl Cancer Inst. 2005 Aug 17;97(16):1221-4. Review.
PMID: 16106027 [PubMed - indexed for MEDLINE]
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