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Helen · 08-31-2006, 10:43 AM

I started Navelbine in June. In July and August my SGPT(ALT) and SGOT(AST) were high for the first time. I had a CT scan in last August 2006 and my liver mets is vaguely seen on the CT scan per the report.
Is it Navelbine that is causing my elevated SGPT and SGOT? My lab results have always been normal even when I was on chemo ( Taxotere and Carboplain) back in July - December 2005. I was in partial remission and just had Herceptin since Jan - June 2006. Should I be concerned? My report also said that "liver is slightly enlarged and perhaps mildly fatty infiltrated". My onc said not to worry but I am ....
May I have your input?
Thank you very much.

Helen

08-31-2006, 10:43 AM	#1
Helen Senior Member Join Date: Sep 2005 Location: Central Valley, CA Posts: 73	SGPT and SGOT high I started Navelbine in June. In July and August my SGPT(ALT) and SGOT(AST) were high for the first time. I had a CT scan in last August 2006 and my liver mets is vaguely seen on the CT scan per the report. Is it Navelbine that is causing my elevated SGPT and SGOT? My lab results have always been normal even when I was on chemo ( Taxotere and Carboplain) back in July - December 2005. I was in partial remission and just had Herceptin since Jan - June 2006. Should I be concerned? My report also said that "liver is slightly enlarged and perhaps mildly fatty infiltrated". My onc said not to worry but I am .... May I have your input? Thank you very much. Helen __________________ Diagnosed May 2005 8 months after giving birth. Stage IV due to a single liver mets. Carbo/Taxotere/ Herceptin combo for 6 months Herceptin/ Navelbine Recurrence on the same liver spot in 7/07 Liver resection 9/07 Tykerb/xeloda 10/22/07 NED since 9/07 and continued Tykerb/xeloda PET/CT in May 2009 show small spot in lungs. Continued Tykerb/xeloda PET/CT in Aug 2009 shows progression on lung nodules (slightly bigger) Onc considering Taxol/avastin