DNA-guided CRISPR system targets RNA and expands Cas12 beyond gene editing

[News]

Researchers developed ?DNA, a DNA-based CRISPR guide that allows Cas12 enzymes to target RNA with high specificity while retaining compatibility with DNA-editing workflows. The platform detected HCV RNA in clinical samples and enabled programmable RNA knockdown, multiplex targeting, and RNA modification in human cells.

More... (https://www.news-medical.net/news/20260518/DNA-guided-CRISPR-system-targets-RNA-and-expands-Cas12-beyond-gene-editing.aspx)