Nguyen
01-17-2023, 11:15 AM
XBB1.5 The most infectious variant to date is becoming dominant in the US. Yet, it seems people are not taking covid seriously anymore. So we have to be even more on-guard. The Jama article below shows we need to be self-inform.
All of the currently (1/17/23) available antibody based regimens do not work against it.
I hope that you have received the bi-valent vaccine booster shot. Limited current data seems to indicates Moderna is better than Pfizer. Regardless, bi-valent booster shot from both Pfizer and Moderna work better as compared to previous booster against XBB1.5.
Note that screening checklist below includes drugs that interact with Paxlovid.
Nguyen
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Getting Treated (Paxlovid) for COVID-19 Shouldn’t Be This Difficult
https://jamanetwork.com/journals/jama/fullarticle/2800108
PAXLOVID Patient Eligibility Screening Checklist Tool for Prescribers
https://www.fda.gov/media/158165/download
COVID-19 Treatment Guidelines
https://www.covid19treatmentguidelines.nih.gov/therapies/
The XBB1.5 COVID-19 variant: 7 questions, answered
https://www.mdanderson.org/cancerwise/the-xbb1-5-covid-19-variant--7-questions--answered.h00-159615489.html
"...5. Why should cancer patients and their caregivers pay particularly close attention to XBB1.5?
XBB1.5 is highly transmissible — and possibly the most transmissible subvariant so far, based on lab studies. That’s due to the specific mutations this one acquired, which make it much more contagious..."
All of the currently (1/17/23) available antibody based regimens do not work against it.
I hope that you have received the bi-valent vaccine booster shot. Limited current data seems to indicates Moderna is better than Pfizer. Regardless, bi-valent booster shot from both Pfizer and Moderna work better as compared to previous booster against XBB1.5.
Note that screening checklist below includes drugs that interact with Paxlovid.
Nguyen
-------
Getting Treated (Paxlovid) for COVID-19 Shouldn’t Be This Difficult
https://jamanetwork.com/journals/jama/fullarticle/2800108
PAXLOVID Patient Eligibility Screening Checklist Tool for Prescribers
https://www.fda.gov/media/158165/download
COVID-19 Treatment Guidelines
https://www.covid19treatmentguidelines.nih.gov/therapies/
The XBB1.5 COVID-19 variant: 7 questions, answered
https://www.mdanderson.org/cancerwise/the-xbb1-5-covid-19-variant--7-questions--answered.h00-159615489.html
"...5. Why should cancer patients and their caregivers pay particularly close attention to XBB1.5?
XBB1.5 is highly transmissible — and possibly the most transmissible subvariant so far, based on lab studies. That’s due to the specific mutations this one acquired, which make it much more contagious..."