No anti-tumor effects seen in adding Zolendraic acid to chemo

[Hopeful]

Abstract:

http://www.abstracts2view.com/sabcs10/view.php?nu=SABCS10L_236

Poster:


(http://</p><p><a href="http://www.abstracts2view.com/sabcs10/viewp.php?nu=P1-11-01" target="_blank">http://www.abstracts2view.com/sabcs10/viewp.php?nu=P1-11-01</a>)http://www.abstracts2view.com/sabcs10/viewp.php?nu=P1-11-01

Hopeful

[Rich66]

Hmmm...maybe according to the lab metrics used. But it might be good to try more than one dose and see how the tumor responds.

Conclusions: No definite evidence of a direct anti-tumour effect of the addition of Z to CT was observed, but potentially relevant biological effects were seen in this small study. The clinical relevance of recovery of cell turnover by D21 with CT+Z is unclear. Studies with more frequent dosing of Z are warranted to exploit any potential anti-angiogenic effect of Z.

Related (http://her2support.org/vbulletin/showthread.php?t=39563)