HER2-Positive Breast Cancer: Beyond Trastuzumab

[Nancy L]

This was an interesting article.

http://www.cancernetwork.com/breast-cancer/content/article/10165/1556186

[Chelee]

Your right Nancy...it is a very interesting article. Thanks so much for posting this.

Chelee

[bejuce]

Yes, thanks for posting! I did find it a bit depressing though:

"Despite the major advance in the therapy of HER2-positive breast cancer represented by this agent, nearly all patients treated with trastuzumab for advanced breast cancer will ultimately experience progression, while a significant proportion of patients receiving this treatment in the setting of early breast cancer will experience disease recurrence."

[Rich66]

But...there seems to be value in continuing H after progression...with cancer stem cell implications. That's more than can be said for a lot of therapies.
I'm surprised they didn't get into the Her2/ER crosstalk (http://her2support.org/vbulletin/showthread.php?t=38998) issue.

[Nancy L]

Rich, I would love a link to the Her2/Er crosstalk debate. Thanks

[Rich66]

http://her2support.org/vbulletin/showthread.php?t=38998