Determination of HER2 amplification - when should chromosome 17 also be determined

[Hopeful]

http://www.abstracts2view.com/sabcs/view.php?nu=SABCS08L_237

Hopeful

[Rich66]

Is it just me or does it seem equivocal FISH and this polysomy 17 issue is being bounced around with no clear recommendations?

[Becky]

They probably need to understand the ramifications of this and possible studies to support what they might be looking for.

I am just commenting that Chromosome 17 is the chromosome BRCA 1 resides. There may be a familial link for those who are Her2+ and have polysomy 17 perhaps? (Just thinking out loud here).

PS - BRCA 2 resides on Chromosome 13