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View Full Version : New Oral Angiogenesis Inhibitor Offers Potential Nontoxic Therapy For A Wide Range Of


Merridith
06-30-2008, 04:38 PM
The first oral, broad-spectrum angiogenesis inhibitor, specially formulated through nanotechnology, shows promising anticancer results....(excerpt)

Because it is nontoxic and can be taken orally, the drug, called Lodamin, may be useful as a preventive therapy for patients at high risk for cancer or as a chronic maintenance therapy for a variety of cancers, preventing tumors from forming or recurring by blocking the growth of blood vessels to feed them....

http://www.sciencedaily.com/releases/2008/06/080630114209.htm

Rich66
01-14-2010, 04:19 AM
In vivo evaluation of microspheres containing the angiogenesis inhibitor, TNP-470, and the metastasis suppression with liver metastatic model implanted neuroblastoma. (http://www.ncbi.nlm.nih.gov/pubmed/19540735?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed _ResultsPanel.Pubmed_RVDocSum&ordinalpos=5)
Yasuda C, Sakata S, Kakinoki S, Takeyama Y, Ohyanagi H, Shiozaki H.
Pathophysiology. 2009 Jun 18. [Epub ahead of print]PMID: 19540735 [PubMed - as supplied by publisher]Related articles (http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=pubmed_pubmed&uid=19540735&ordinalpos=5)

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Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics. (http://www.ncbi.nlm.nih.gov/pubmed/19381291?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed _ResultsPanel.Pubmed_RVDocSum&ordinalpos=6)
Segal E, Pan H, Ofek P, Udagawa T, Kopecková P, Kopecek J, Satchi-Fainaro R.
PLoS One. 2009;4(4):e5233. Epub 2009 Apr 21.PMID: 19381291 [PubMed - indexed for MEDLINE]Related articles (http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=link&linkname=pubmed_pubmed&uid=19381291&ordinalpos=6)Free article (http://www.ncbi.nlm.nih.gov/pubmed/19381291?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed _ResultsPanel.Pubmed_RVDocSum&ordinalpos=6&log$=free)

Ellie F
01-14-2010, 06:00 AM
Aaagh! Frustration again. Another promising strategy but NO clinical trials. These things take soooo long!

Ellie